Shyong Olivia, Alfakhri Nora, Bates Sara V, Carroll Ryan W, Gallagher Krista, Huang Lena, Madhavan Vandana, Murphy Sarah A, Okrzesik Sylvia A, Yager Phoebe H, Yonker Lael M, Lok Josephine
Department of Pediatrics, Pediatric Critical Care Medicine, Massachusetts General Hospital, Boston, MA, USA.
Harvard Medical School, Boston, MA, USA.
J Intensive Care Med. 2025 Mar 17:8850666251320558. doi: 10.1177/08850666251320558.
Multisystem Inflammatory Syndrome in Children: A Comprehensive Review over the Past Five Years This review explores many facets of Multisystem Inflammatory Syndrome in Children (MIS-C) over the previous 5 years. In the time since the COVID 19 pandemic gripped our medical systems, we can now explore the data that has been collected from the previous years. The literature has allowed us to better understand the impact of COVID 19 and the post illness occurrence of a severe systemic inflammatory disease on our youngest patient populations. This paper will outline the pathophysiology of MIS-C, the treatments utilized, short and long-term patient outcomes including epidemiological factors.
过去五年的全面综述 本综述探讨了过去5年中儿童多系统炎症综合征（MIS-C）的多个方面。自新冠疫情席卷我们的医疗系统以来，我们现在可以探究过去几年收集到的数据。这些文献使我们能够更好地了解新冠病毒以及患病后一种严重的全身性炎症疾病对我们最年幼患者群体的影响。本文将概述MIS-C的病理生理学、所采用的治疗方法、患者的短期和长期预后，包括流行病学因素。
