Han Jing, Song Hong, Wang Linlin, Bi Liuna, Yang Feng
School of Nursing, Xuzhou Medical University, Xuzhou, China.
The Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.
Psychooncology. 2025 Mar;34(3):e70134. doi: 10.1002/pon.70134.
Children with leukemia and their caregivers have negative experiences such as pain, fear, and sleep disturbances when receiving invasive procedures. The purpose of this study was to evaluate the effects of a biofeedback intervention on negative emotions and sleep quality for children with leukemia receiving invasive procedures and their caregivers.
A randomized controlled study involving 80 child-caregiver dyads was conducted, and dyads were randomly assigned to intervention (n = 40) and control (n = 40) groups. Both groups received health education, while the intervention group additionally received a 4-unit biofeedback intervention. Outcome measures compared at baseline (T0), post-intervention (T1), and 4-week follow-up (T2), included validated measures of pain, fear, worry, sleep quality in children, and anxiety, depression, and sleep quality in caregivers.
At T1 and T2, the scores of children's pain and fear in the intervention group were significantly lower than those in the control group (all p < 0.05). The significant group effects on children's pain (F = 6.064, p = 0.015) and fear (F = 15.532, p < 0.001) indicated that the intervention group had significantly lower scores in pain and fear compared to the control group. At T1 and T2, caregivers in the intervention group had significantly lower anxiety scores and significantly higher sleep quality than those in the control group (all p < 0.05). The significant group effects on anxiety (F = 10.124, p = 0.002) and sleep quality (F = 5.983, p = 0.015) suggested that the intervention group had significantly lower scores in anxiety and higher sleep quality in comparison to the control group.
The biofeedback intervention demonstrated significant efficacy in alleviating the pain, and fear experienced by children with leukemia during invasive procedures, concurrently relieving their caregivers' anxiety and improving sleep quality. This research furnishes compelling evidence substantiating the effectiveness of biofeedback interventions in alleviating negative emotions in children with leukemia undergoing invasive treatments, as well as in their caregivers.
ChiCTR2300075306.
白血病患儿及其照料者在接受侵入性操作时会经历疼痛、恐惧和睡眠障碍等负面体验。本研究旨在评估生物反馈干预对接受侵入性操作的白血病患儿及其照料者负面情绪和睡眠质量的影响。
进行了一项随机对照研究，涉及80对儿童-照料者二元组，二元组被随机分配到干预组（n = 40）和对照组（n = 40）。两组均接受健康教育，而干预组还额外接受了4个单元的生物反馈干预。在基线（T0）、干预后（T1）和4周随访（T2）时比较的结果指标包括儿童疼痛、恐惧、担忧、睡眠质量以及照料者焦虑、抑郁和睡眠质量的有效测量指标。
在T1和T2时，干预组儿童的疼痛和恐惧得分显著低于对照组（所有p < 0.05）。对儿童疼痛（F = 6.064，p = 0.015）和恐惧（F = 15.532，p < 0.001）的显著组效应表明，干预组的疼痛和恐惧得分显著低于对照组。在T1和T2时，干预组照料者的焦虑得分显著低于对照组，睡眠质量显著高于对照组（所有p < 0.05）。对焦虑（F = 10.124，p = 0.002）和睡眠质量（F = 5.983，p = 0.015）的显著组效应表明，干预组的焦虑得分显著低于对照组，睡眠质量高于对照组。
生物反馈干预在减轻白血病患儿在侵入性操作过程中所经历的疼痛和恐惧方面显示出显著疗效，同时缓解了其照料者的焦虑并改善了睡眠质量。本研究提供了有力证据，证实了生物反馈干预在减轻接受侵入性治疗的白血病患儿及其照料者负面情绪方面的有效性。
ChiCTR2300075306。
