Suzuki T, Hirota M, Hoshino H, Yamasaku F, Terada I
Gan No Rinsho. 1985 Apr;31(4):434-40.
A 79-year-old woman with primary liposarcoma of the heart, an extremely rare malignancy, coexistent with Brenner tumor was reported. The histological features of the sarcoma on the routine histological slides were so varied that it was necessary to differentiate the histology from that of malignant fibrous histiocytoma or pleomorphic rhabdomyosarcoma. Most of the tumor cells including fibroblastic and bizarre giant cells, however, were stained intensely with histochemical methods for lipids and consequently diagnosed as pleomorphic liposarcoma originated from the epicardium. Electron microscopically, lipid droplets were demonstrated in the cytoplasm of the tumor cells, supporting the histological diagnosis. No distant or nodal metastases were noted.
报道了一名79岁女性，患有心脏原发性脂肪肉瘤（一种极其罕见的恶性肿瘤），同时合并有勃勒纳瘤。常规组织学切片上肉瘤的组织学特征差异很大，因此有必要将其组织学与恶性纤维组织细胞瘤或多形性横纹肌肉瘤相鉴别。然而，大多数肿瘤细胞，包括成纤维细胞和奇异巨细胞，经脂质组织化学方法染色后呈强阳性，因此诊断为起源于心外膜的多形性脂肪肉瘤。电子显微镜下，肿瘤细胞的细胞质中可见脂滴，支持组织学诊断。未发现远处或淋巴结转移。
