Demir Mehmet Ali, Çolak Tahsin, Özcan Cumhur, İnan Hüseyin Oğuzhan, Güler Erkan
Mersin University School of Medicine, Mersin, Turkey.
Lasers Med Sci. 2025 Mar 18;40(1):145. doi: 10.1007/s10103-025-04409-8.
This study aimed to compare laser application with sinus curettage against only sinus curettage in the treatment of pilonidal sinus disease (PSD) in terms of postoperative complications, wound healing, and recurrence. Additionally, we aimed to investigate factors associated with wound healing and recurrence after PSD surgery.
This study included patients diagnosed with PSD between February 2019, and September 2022. The patients were randomly assigned to either the laser + curettage (L/C; n = 40) group or the curettage-only (C; n = 40) group. The following data were collected: demographic and anthropometric information, smoking status, comorbidities, number of PSD-related orifices, complicated or uncomplicated disease, prior recurrence, postoperative findings, wound healing problems within 30 days postoperatively, and recurrence within 6 months postoperatively.
The L/C and C groups were similar in terms of age and sex distribution. The groups had similar results for postoperative pain, discharge, bleeding, wound healing problems at 30 days, and recurrence at 6 months. Multivariable logistic regression revealed that, high weight and higher orifice count were independently associated with wound healing problems. Additionally, high weight, higher orifice count and prior recurrence were independently associated with recurrence.
Combined curettage and laser therapy showed non-significant but broad benefits over curettage alone, but statistical significance was not achieved in any of the adverse findings, as well as wound healing and recurrence. Higher body weight and higher orifice count were associated with both poor wound healing and recurrence, while prior recurrence was another factor associated with recurrence at 6 months.
本研究旨在比较激光联合鼻窦刮除术与单纯鼻窦刮除术治疗藏毛窦疾病(PSD)在术后并发症、伤口愈合及复发方面的差异。此外,我们还旨在研究PSD手术后与伤口愈合及复发相关的因素。
本研究纳入了2019年2月至2022年9月期间被诊断为PSD的患者。患者被随机分为激光+刮除术(L/C;n = 40)组或单纯刮除术(C;n = 40)组。收集了以下数据:人口统计学和人体测量学信息、吸烟状况、合并症、PSD相关窦口数量、疾病复杂或不复杂情况、既往复发情况、术后结果、术后30天内的伤口愈合问题以及术后6个月内的复发情况。
L/C组和C组在年龄和性别分布方面相似。两组在术后疼痛、引流、出血、30天时的伤口愈合问题以及6个月时的复发情况方面结果相似。多变量逻辑回归显示,高体重和较高的窦口数量与伤口愈合问题独立相关。此外,高体重、较高的窦口数量和既往复发与复发独立相关。
刮除术联合激光治疗相对于单纯刮除术显示出虽不显著但广泛的益处,但在任何不良结果以及伤口愈合和复发方面均未达到统计学意义。较高的体重和较高的窦口数量与伤口愈合不良和复发均相关,而既往复发是术后6个月复发的另一个相关因素。