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Nitrate ameliorates myelin loss and cognitive impairment in Alzheimer's disease through upregulation of neuronal sialin and subsequent inhibition of TPPP phosphorylation.

作者信息

Chen Xinyue, Hu Geng, Chang Lirong, Li Xiaoyu, Tang Yi, Wu Yan, Zhang Ran, Zhang Chunmei, Wang Jinsong, Wang Xue, Wang Songlin

机构信息

Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Beijing Laboratory of Oral Health, Capital Medical University, Beijing 100069, China.

Key Laboratory of Big Data-Based Precision Medicine, School of Engineering Medicine, Beihang University, Beijing 100191, China.

出版信息

Sci Bull (Beijing). 2025 Apr 30;70(8):1224-1229. doi: 10.1016/j.scib.2025.03.017. Epub 2025 Mar 9.

DOI:
10.1016/j.scib.2025.03.017
PMID:40102090
Abstract
摘要

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Role of oral and gut microbiomes in enterosalivary nitrate metabolism and their effects on systemic disease.口腔和肠道微生物群在肠-唾液硝酸盐代谢中的作用及其对全身性疾病的影响。
Front Cell Infect Microbiol. 2025 Jul 3;15:1612223. doi: 10.3389/fcimb.2025.1612223. eCollection 2025.