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伪装成胰腺原发性神经内分泌肿瘤的转移性滑膜肉瘤:一个诊断难题。

Metastatic synovial sarcoma masquerading as primary neuroendocrine tumor of pancreas: a diagnostic conundrum.

作者信息

Jacob Sherrin, Thirunavukkarasu Balamurugan, Yadav Rajni, Gupta Anany, Agarwal Samagra, Shamim Shamim A, Rastogi Sameer, Barwad Adarsh, Jain Deepali

机构信息

Department of Pathology, All India Institute of Medical Sciences, New Delhi, 110029, India.

Gastroenterology, All India Institute of Medical Sciences, New Delhi, India.

出版信息

Clin J Gastroenterol. 2025 Jun;18(3):499-505. doi: 10.1007/s12328-025-02110-5. Epub 2025 Mar 19.

Abstract

Metastatic sarcomas to the pancreas are extremely rare, with poor survival rates. Therefore, rapid diagnosis and differentiation from primary malignant tumors of pancreas thereby guiding the treatment is indispensable. Endoscopic ultrasound-guided fine needle biopsy (EUS-FNB) is the current diagnostic modality of choice for pancreatic tumor sampling with promising results. Definitive pathologic diagnosis requires adequate tissue for performing ancillary studies. We present a rare case of metastatic synovial sarcoma in the pancreas in an elderly male to endorse the utility of EUS-FNB with imprint cytology as a rapid and effective diagnostic tool.

摘要

胰腺转移性肉瘤极为罕见,生存率低。因此,快速诊断并与胰腺原发性恶性肿瘤相鉴别从而指导治疗是必不可少的。内镜超声引导下细针穿刺活检(EUS-FNB)是目前胰腺肿瘤采样的首选诊断方式,效果良好。明确的病理诊断需要足够的组织来进行辅助研究。我们报告一例老年男性胰腺转移性滑膜肉瘤的罕见病例,以支持EUS-FNB联合印片细胞学检查作为一种快速有效的诊断工具的实用性。

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