Bogusz M, Bialka J, de Zeeuw R A, Franke J P
J Anal Toxicol. 1985 May-Jun;9(3):139-40. doi: 10.1093/jat/9.3.139.
Correction of crude thin layer chromatographic data usually enables a reliable comparison with reference data bases. However, when the correction standards are not spotted in the right positions, the calculation may produce false results if anomalous migration occurs. This was observed in the case of acidic and neutral drugs developed in the chloroform-methanol (9:1) system.
对粗制薄层色谱数据进行校正通常能够与参考数据库进行可靠的比较。然而,当校正标准品未点在正确位置时,如果发生异常迁移,计算可能会产生错误结果。在氯仿 - 甲醇(9:1)系统中展开的酸性和中性药物的情况下观察到了这种情况。