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一例无肥厚型心肌病的腱索收缩期前向运动误诊为急性冠状动脉综合征的病例报告。

A case report of chordal systolic anterior motion without hypertrophic cardiomyopathy misdiagnosed with acute coronary syndrome.

作者信息

Haji Aghajani Mohammad, Omidi Fateme, Hamneshin Behbahani Reza, Ebrahimi Moein

机构信息

Department of Cardiology, School of Medicine, Imam Hossein Educational Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Clinical Research Development Center, Imam Hossein Educational Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

出版信息

ARYA Atheroscler. 2024;20(6):1-5. doi: 10.48305/arya.2024.42681.2967.

DOI:10.48305/arya.2024.42681.2967
PMID:40103628
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11913459/
Abstract

Chordal systolic anterior motion (SAM) refers to the anterior motion of the mitral valve towards the left ventricular outflow tract (LVOT) that occurs during systole. Chordal SAM is a potentially fatal condition. Chordal SAM is linked to an elevated risk of sudden death and can lead to significant obstruction of the left ventricular outflow tract (LVOT) and mitral regurgitation. It is crucial to acknowledge and consider this phenomenon when assessing individuals experiencing dyspnea and chest discomfort. By doing so, unnecessary therapies related to heart failure and heart attack might be avoided. Ensuring timely diagnosis is crucial in order to prevent unnecessary and potentially dangerous therapies that can aggravate LVOT obstruction and lead to hemodynamic instability. In this paper, we present a 47-year-old woman who experienced sudden chest pain and dyspnea. The patient had a history of hypertension and previous myocardial infarction. ST-elevation was observed in the first ECG. The primary treatment for acute coronary syndrome was initiated. Coronary angiography demonstrated that coronary vessels were not obstructed. The diagnosis of chordal SAM was initially overlooked during the echocardiography, but it was later identified during a subsequent echocardiography after cardiac catheterization. When using beta-blockers, her clinical condition improved.

摘要

腱索收缩期前向运动(SAM)是指二尖瓣在收缩期朝向左心室流出道(LVOT)的前向运动。腱索SAM是一种潜在的致命病症。腱索SAM与猝死风险升高相关,可导致左心室流出道(LVOT)严重梗阻及二尖瓣反流。在评估出现呼吸困难和胸部不适的个体时,认识并考虑到这种现象至关重要。这样做可以避免与心力衰竭和心脏病发作相关的不必要治疗。确保及时诊断对于预防可能加重LVOT梗阻并导致血流动力学不稳定的不必要且潜在危险的治疗至关重要。在本文中,我们介绍了一名47岁突发胸痛和呼吸困难的女性。该患者有高血压病史和既往心肌梗死病史。首次心电图观察到ST段抬高。启动了急性冠状动脉综合征的初始治疗。冠状动脉造影显示冠状动脉血管未梗阻。在超声心动图检查期间最初忽略了腱索SAM的诊断,但在心脏导管检查后的后续超声心动图检查中后来得以确诊。使用β受体阻滞剂后,她的临床状况有所改善。

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本文引用的文献

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Mitral Regurgitation and Left Ventricular Outflow Tract Obstruction: Confluence of Challenges for Transcatheter Treatment.二尖瓣反流与左心室流出道梗阻:经导管治疗面临的挑战汇总
Rev Cardiovasc Med. 2024 Apr 3;25(4):134. doi: 10.31083/j.rcm2504134. eCollection 2024 Apr.
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Chordal Systolic Anterior Motion of the Mitral Valve in Dextro-Looped Transposition of the Great Vessels After Mustard Procedure.大动脉转位术后 Mustard 手术后二尖瓣腱索收缩期前向运动呈顺钟向转位。
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The Disappearing Murmur: Systolic Anterior Motion of the Mitral Valve Leaflet in a Non-hypertrophic Cardiomyopathy Patient.消失的杂音:非肥厚型心肌病患者二尖瓣叶收缩期前向运动
Cureus. 2018 Jun 21;10(6):e2855. doi: 10.7759/cureus.2855.
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Clinical features of the systolic anterior motion of the mitral valve among patients without hypertrophic cardiomyopathy.非肥厚型心肌病患者二尖瓣收缩期前向运动的临床特征
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J Thorac Cardiovasc Surg. 2012 Apr;143(4 Suppl):S2-7. doi: 10.1016/j.jtcvs.2012.01.063.
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Eur J Cardiothorac Surg. 2012 Jun;41(6):1260-70. doi: 10.1093/ejcts/ezr232. Epub 2012 Jan 18.
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