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二尖瓣修复术后收缩期前向运动的风险因素和进展。

Risk factors and progression of systolic anterior motion after mitral valve repair.

机构信息

Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, Minn.

Department of Cardiovascular Surgery, Mayo Clinic, Rochester, Minn.

出版信息

J Thorac Cardiovasc Surg. 2021 Aug;162(2):567-577. doi: 10.1016/j.jtcvs.2019.12.106. Epub 2020 Feb 16.

DOI:10.1016/j.jtcvs.2019.12.106
PMID:32173099
Abstract

OBJECTIVES

The phenomenon of systolic anterior motion (SAM) of the mitral valve (MV) was discovered 50 years ago, but to date only a few studies have identified risk factors for SAM following mitral repair. There are limited data on the necessity of surgical reintervention on the MV once SAM is discovered by intraoperative transesophageal echocardiography. We sought to identify predictors of SAM in a large cohort of consecutive patients, assess the rate of early reintervention on the MV to address SAM, and follow the progression of SAM postdischarge.

METHODS

Analysis of electronically stored echocardiographic exams of adults who underwent MV repair in a recent decade.

RESULTS

Following MV repair, the incidence of SAM immediately after cardiopulmonary bypass was 13% (98 of 761 patients). Multivariable analysis revealed several preoperative risk factors of SAM development and progression, including a lower ratio of anterior to posterior leaflets heights, younger age, lower end-systolic left ventricular volume, presence of bileaflet prolapse, and male sex. SAM was managed conservatively in 91 patients (93%) and surgically in 7 patients (7%). In a majority of patients (70 of 98 patients [71%]) SAM resolved before hospital discharge.

CONCLUSIONS

Transesophageal echocardiography findings associated with SAM were excessive height of posterior to anterior mitral leaflet, smaller left ventricular end-systolic volume, and bileaflet prolapse. Conservative management of SAM was usually successful, and persistent hemodynamically significant SAM was uncommon. Prophylactic modification of the surgical technique to avoid SAM seems unnecessary for all but those at highest risk for developing SAM.

摘要

目的

二尖瓣收缩期前向运动(SAM)现象于 50 年前被发现,但迄今为止,仅有少数研究确定了二尖瓣修复术后 SAM 的危险因素。对于术中经食管超声心动图发现 SAM 后是否需要对二尖瓣进行再次手术干预,相关数据有限。我们试图在一个大型连续患者队列中确定 SAM 的预测因素,评估早期对 MV 进行再干预以解决 SAM 的发生率,并随访出院后 SAM 的进展情况。

方法

对最近十年接受二尖瓣修复术的成人进行电子存储的超声心动图检查分析。

结果

体外循环后二尖瓣修复后 SAM 的发生率为 13%(761 例患者中有 98 例)。多变量分析显示 SAM 发生和进展的几个术前危险因素,包括前瓣与后瓣高度的比值较低、年龄较小、左心室收缩末期容积较低、双瓣叶脱垂以及男性。91 例(93%)患者 SAM 采用保守治疗,7 例(7%)患者采用手术治疗。在大多数患者(98 例患者中的 70 例[71%])中,SAM 在出院前得到解决。

结论

与 SAM 相关的经食管超声心动图发现为后瓣与前瓣二尖瓣高度过高、左心室收缩末期容积较小和双瓣叶脱垂。SAM 的保守治疗通常是成功的,持续性血流动力学显著 SAM 并不常见。对于那些发生 SAM 风险最高的患者,除了那些患者之外,预防性修改手术技术以避免 SAM 似乎是不必要的。

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