• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

磁性氮掺杂碳纳米管负载氧化铜作为生物相容性深共熔溶剂中腈类与芳基卤化物芳基化反应的催化剂

Magnetic N-doped CNT stabilized CuO as a catalyst for -arylation of nitriles and aryl halides in a biocompatible deep eutectic solvent.

作者信息

Alizadeh Mohadeseh, Salamatmanesh Arefe, Nejad Masoumeh Jadidi, Heydari Akbar

机构信息

Chemistry Department, Tarbiat Modares University P.O. Box 14155-4838 Tehran Iran

Department of Chemistry, Isfahan University of Technology Isfahan 84156-83111 Iran

出版信息

RSC Adv. 2025 Mar 18;15(11):8195-8206. doi: 10.1039/d5ra00849b. eCollection 2025 Mar 17.

DOI:10.1039/d5ra00849b
PMID:40103972
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11915213/
Abstract

This study documented the hydrolysis of nitriles by copper(i) oxide immobilized on nitrogen-doped carbon nanotubes (N-CNT/FeO-CuO) to yield corresponding amides in the presence of a deep eutectic solvent (ChOH/Gly). Furthermore, the aforementioned catalyst can facilitate the coupling reaction between aryl halides and amides derived by nitrile hydrolysis. Consequently, the integration of two copper-catalyzed processes can efficiently provide -aryl amides. Choline hydroxide in a deep eutectic solvent serves as a cost-effective organic catalyst in nitrie hydrolysis by forming hydrogen bonds with nitrile, thereby activating it. The catalyst generated higher to satisfactory product yields. One of the special benefits of the catalyst is that it can be restored through the addition of an external magnetic field.

摘要

本研究记录了负载在氮掺杂碳纳米管（N-CNT/FeO-CuO）上的氧化亚铜在深共熔溶剂（ChOH/Gly）存在下对腈进行水解以生成相应酰胺的过程。此外，上述催化剂可促进芳基卤化物与腈水解衍生的酰胺之间的偶联反应。因此，两个铜催化过程的整合能够高效地提供芳基酰胺。深共熔溶剂中的氢氧化胆碱通过与腈形成氢键从而活化腈，在腈水解中作为一种经济高效的有机催化剂。该催化剂产生了较高至令人满意的产物收率。该催化剂的一个特殊优点是它可以通过施加外部磁场来恢复。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2c9/11915213/e1a5d0dfb2fc/d5ra00849b-f9.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2c9/11915213/069ccce521b1/d5ra00849b-s1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2c9/11915213/940322009fa0/d5ra00849b-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2c9/11915213/9a350aff2009/d5ra00849b-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2c9/11915213/13c061219164/d5ra00849b-f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2c9/11915213/15b27a042b09/d5ra00849b-f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2c9/11915213/a93c94dd1061/d5ra00849b-f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2c9/11915213/5707949ac0a5/d5ra00849b-f6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2c9/11915213/84bd94810932/d5ra00849b-f7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2c9/11915213/6a22efd684c5/d5ra00849b-f8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2c9/11915213/57dff8b76a6b/d5ra00849b-s2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2c9/11915213/e1a5d0dfb2fc/d5ra00849b-f9.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2c9/11915213/069ccce521b1/d5ra00849b-s1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2c9/11915213/940322009fa0/d5ra00849b-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2c9/11915213/9a350aff2009/d5ra00849b-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2c9/11915213/13c061219164/d5ra00849b-f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2c9/11915213/15b27a042b09/d5ra00849b-f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2c9/11915213/a93c94dd1061/d5ra00849b-f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2c9/11915213/5707949ac0a5/d5ra00849b-f6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2c9/11915213/84bd94810932/d5ra00849b-f7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2c9/11915213/6a22efd684c5/d5ra00849b-f8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2c9/11915213/57dff8b76a6b/d5ra00849b-s2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2c9/11915213/e1a5d0dfb2fc/d5ra00849b-f9.jpg

相似文献

1
Magnetic N-doped CNT stabilized CuO as a catalyst for -arylation of nitriles and aryl halides in a biocompatible deep eutectic solvent.磁性氮掺杂碳纳米管负载氧化铜作为生物相容性深共熔溶剂中腈类与芳基卤化物芳基化反应的催化剂
RSC Adv. 2025 Mar 18;15(11):8195-8206. doi: 10.1039/d5ra00849b. eCollection 2025 Mar 17.
2
Efficient base- and ligand-free palladium catalysed -arylation of phenols in choline chloride:triethanolamine as a reusable deep eutectic solvent.在氯化胆碱：三乙醇胺这种可重复使用的低共熔溶剂中，实现高效的无碱和无配体钯催化酚类的芳基化反应。
R Soc Open Sci. 2024 Jun 5;11(6):240045. doi: 10.1098/rsos.240045. eCollection 2024 Jun.
3
Reusable Cu2O/PPh3/TBAB system for the cross-couplings of aryl halides and heteroaryl halides with terminal alkynes.用于芳基卤化物和杂芳基卤化物与末端炔烃交叉偶联的可重复使用的Cu2O/PPh3/TBAB体系。
J Org Chem. 2007 Aug 3;72(16):6294-7. doi: 10.1021/jo070538o. Epub 2007 Jul 6.
4
Copper-Catalyzed Coupling Reaction of (Hetero)Aryl Chlorides and Amides.铜催化的（杂）芳基氯代物和酰胺的偶联反应。
Org Lett. 2017 Sep 15;19(18):4864-4867. doi: 10.1021/acs.orglett.7b02326. Epub 2017 Aug 31.
5
Copper/amino acid catalyzed cross-couplings of aryl and vinyl halides with nucleophiles.铜/氨基酸催化的芳基卤化物和乙烯基卤化物与亲核试剂的交叉偶联反应。
Acc Chem Res. 2008 Nov 18;41(11):1450-60. doi: 10.1021/ar8000298.
6
Polythiophene-functionalized magnetic carbon nanotube-supported copper(I) complex: a novel and retrievable heterogeneous catalyst for the "Phosphine- and Palladium-Free" Suzuki-Miyaura cross-coupling reaction.聚噻吩功能化磁性碳纳米管负载的铜（I）配合物：一种新型可回收的非均相催化剂，用于“无膦和钯”的 Suzuki-Miyaura 交叉偶联反应。
Mol Divers. 2020 Nov;24(4):1125-1137. doi: 10.1007/s11030-019-10016-x. Epub 2019 Nov 22.
7
Magnetic Ugi-functionalized graphene oxide complexed with copper nanoparticles: Efficient catalyst toward Ullman coupling reaction in deep eutectic solvents.磁性 Ugi 功能化氧化石墨烯与铜纳米粒子复合物：在深共晶溶剂中用于 Ullman 偶联反应的高效催化剂。
J Colloid Interface Sci. 2018 Jan 15;510:384-394. doi: 10.1016/j.jcis.2017.09.089. Epub 2017 Sep 23.
8
Ligand-Free Copper-Catalyzed Ullmann-Type C-O Bond Formation in Non-Innocent Deep Eutectic Solvents under Aerobic Conditions.有氧条件下在非惰性深共熔溶剂中无配体铜催化的乌尔曼型碳-氧键形成反应
ChemSusChem. 2022 Jan 10;15(1):e202102211. doi: 10.1002/cssc.202102211. Epub 2021 Dec 6.
9
N-(1-Oxy-2-picolyl)oxalamic acids as a new type of O,O-ligands for the Cu-catalyzed N-arylation of azoles with aryl halides in water or organic solvent.N-(1-氧代-2-吡啶甲基)草氨酸作为一种新型的O,O-配体，用于在水或有机溶剂中铜催化唑类与芳基卤化物的N-芳基化反应。
Org Biomol Chem. 2015 Apr 7;13(13):4101-14. doi: 10.1039/c5ob00045a.
10
Proposal for halogen atom transfer mechanism for Ullmann O-arylation of phenols with aryl halides.酚类与卤代芳烃的乌尔姆曼 O-芳基化的卤原子转移机理的建议。
Dalton Trans. 2012 Dec 7;41(45):13832-40. doi: 10.1039/c2dt31500a. Epub 2012 Aug 28.

本文引用的文献

1
Visible light-induced photoredox catalyzed C-N coupling of amides with alcohols.可见光诱导的光氧化还原催化酰胺与醇的C-N偶联反应。
RSC Adv. 2022 Dec 8;12(54):35221-35226. doi: 10.1039/d2ra07065k. eCollection 2022 Dec 6.
2
Scope and Mechanism of a True Organocatalytic Beckmann Rearrangement with a Boronic Acid/Perfluoropinacol System under Ambient Conditions.在环境条件下，硼酸/全氟频哪醇体系中真正的有机催化贝克曼重排的范围和机制。
J Am Chem Soc. 2018 Apr 18;140(15):5264-5271. doi: 10.1021/jacs.8b01618. Epub 2018 Apr 6.
3
Mechanism of Amide Bond Formation from Carboxylic Acids and Amines Promoted by 9-Silafluorenyl Dichloride Derivatives.9-硅杂芴二氯衍生物促进的羧酸和胺形成酰胺键的机理。
J Org Chem. 2017 Sep 1;82(17):9087-9096. doi: 10.1021/acs.joc.7b01637. Epub 2017 Aug 17.
4
Encapsulation of Fe3O4 Nanoparticles into N, S co-Doped Graphene Sheets with Greatly Enhanced Electrochemical Performance.将Fe3O4纳米颗粒封装到具有大大增强的电化学性能的N、S共掺杂石墨烯片中。
Sci Rep. 2016 Jun 14;6:27957. doi: 10.1038/srep27957.
5
Catalytic amide formation from non-activated carboxylic acids and amines.非活化羧酸和胺的催化酰胺形成。
Chem Soc Rev. 2014 Apr 21;43(8):2714-42. doi: 10.1039/c3cs60345h. Epub 2014 Jan 15.
6
Aromatic amide foldamers: structures, properties, and functions.芳香酰胺折叠体：结构、性质及功能。
Chem Rev. 2012 Oct 10;112(10):5271-316. doi: 10.1021/cr300116k. Epub 2012 Aug 7.
7
Flexible multilevel resistive memory with controlled charge trap B- and N-doped carbon nanotubes.具有可控电荷俘获的柔性多级电阻式存储器 B、N 掺杂碳纳米管。
Nano Lett. 2012 May 9;12(5):2217-21. doi: 10.1021/nl204039q. Epub 2012 Apr 20.
8
Nitrogen-doped multiwall carbon nanotubes for lithium storage with extremely high capacity.掺氮多壁碳纳米管具有超高容量的锂存储性能。
Nano Lett. 2012 May 9;12(5):2283-8. doi: 10.1021/nl3000908. Epub 2012 Apr 4.
9
Workfunction-tunable, N-doped reduced graphene transparent electrodes for high-performance polymer light-emitting diodes.工作函数可调、N 掺杂还原氧化石墨烯透明电极用于高性能聚合物发光二极管。
ACS Nano. 2012 Jan 24;6(1):159-67. doi: 10.1021/nn203176u. Epub 2011 Dec 13.
10
Nitrogen-doped graphene for high-performance ultracapacitors and the importance of nitrogen-doped sites at basal planes.氮掺杂石墨烯在高性能超级电容器中的应用以及基底平面中氮掺杂位点的重要性。
Nano Lett. 2011 Jun 8;11(6):2472-7. doi: 10.1021/nl2009058. Epub 2011 May 19.