Wetmore S J, Key J M, Suen J Y
Laryngoscope. 1985 Jul;95(7 Pt 1):798-801.
Carbon dioxide laser surgery has become the treatment of choice for laryngeal papillomatosis. The purpose of this study was to determine the type, incidence, and severity of complications that occur with laser microlaryngoscopy for a disease that often requires multiple operations. Forty patients with laryngeal papillomatosis underwent a total of 222 carbon dioxide laser laryngoscopies over the 6 1/2-year period from June 1977 through December 1983. The results showed that 13 patients sustained a total of 23 separate complications. Intraoperative complications consisted of one episode of bilateral pneumothorax and one episode of cervical subcutaneous emphysema, both associated with the use of jet ventilation anesthesia, and one episode of a loosened tooth in a child with carious teeth. The delayed complications consisted of 10 patients with anterior laryngeal webbing, 2 patients with posterior webbing, 6 patients with laryngeal edema or fibrosis, and one episode each of prolonged dysphagia and tracheal foreign body. No airway fires occurred. Only 2 of 28 patients who had 5 or fewer laser laryngoscopies developed complications, but 11 or 12 patients undergoing 6 or more laser operations had complications. In summary, although the incidence of life threatening complications was low, the occurrence of minor complications such as small anterior glottic webs and persistent edema was relatively high, especially in those patients who required multiple laser laryngoscopies.
二氧化碳激光手术已成为喉乳头状瘤病的首选治疗方法。本研究的目的是确定对于这种通常需要多次手术的疾病,在激光显微喉镜检查中出现的并发症的类型、发生率和严重程度。从1977年6月至1983年12月的6年半时间里,40例喉乳头状瘤病患者共接受了222次二氧化碳激光喉镜检查。结果显示,13例患者共出现23种不同的并发症。术中并发症包括一例双侧气胸和一例颈部皮下气肿,均与喷射通气麻醉的使用有关,以及一例患有龋齿的儿童牙齿松动。延迟并发症包括10例前喉蹼、2例后喉蹼、6例喉水肿或纤维化,以及各一例吞咽困难延长和气管异物。未发生气道火灾。在接受5次或更少激光喉镜检查的28例患者中,只有2例出现并发症,但接受6次或更多激光手术的11或12例患者出现了并发症。总之,虽然危及生命的并发症发生率较低,但诸如小的前声门蹼和持续性水肿等轻微并发症的发生率相对较高,尤其是在那些需要多次激光喉镜检查的患者中。