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澳大利亚医疗保健框架下垂体手术的发展历程

The Evolution of Pituitary Surgery in an Australian Health Care Framework.

作者信息

Candy Nicholas G, Jukes Alistair K, Ooi Eng H, Valentine Rowan, Vrodos Nick, Santoreneos Stephen, Floreani Steve, Wormald Peter-John, Psaltis Alkis J

机构信息

Department of Surgery - Otolaryngology, Head and Neck Surgery, The University of Adelaide, Basil Hetzel Institute for Translational Research, Woodville South, Adelaide, Australia.

Department of Neurosurgery, Royal Adelaide Hospital, Adelaide, Australia.

出版信息

J Neurol Surg B Skull Base. 2024 Apr 15;86(2):221-228. doi: 10.1055/s-0044-1786044. eCollection 2025 Apr.

Abstract

The outcomes in pituitary surgery have dramatically changed over the past 130 years. Endoscopic endonasal transsphenoidal approaches are now an accepted method for operating on pituitary tumors, a skillset which takes time to develop. The Australian health care framework provides a unique mixture of public and private care for a geographically dispersed population. In this article, we aim to examine how outcomes for patients in South Australia changed as endoscopic pituitary surgery was adopted and how the Australian health care framework influenced the development of a skull base team.  The case notes of all patients undergoing pituitary surgery between 2006 and 2020 in South Australia. All patients treated by this author group were included.  A total of 428 pituitary adenomas were surgically treated. Overall, 182 out of 249 patients (70%) had a complete resection with no recurrence at follow-up, and 49 patients (19%) had a residual that was observed and did not require treatment. Therefore, 89% of patients between the years 2006 and 2020 did not require any further treatment following their pituitary surgery. Upon examination of the 142 patients with functional adenomas, 112 (79%) patients had no recurrence in hormonal dysfunction following surgery, and the remaining 30 (21%) patients required further treatment.  We have demonstrated that acceptable outcomes can be achieved in a low-to-moderate volume setting across multiple hospitals when a coordinated effort is made to consolidate these cases within a small group of subspeciality-trained surgeons, as opposed to a more generalist approach.

摘要

在过去的130年里,垂体手术的结果发生了巨大变化。内镜下经鼻蝶窦入路现已成为垂体肿瘤手术的一种公认方法,而掌握这项技能需要时间。澳大利亚的医疗保健框架为地域分散的人群提供了独特的公共和私人医疗服务组合。在本文中,我们旨在研究南澳大利亚州患者采用内镜垂体手术后的结果如何变化,以及澳大利亚的医疗保健框架如何影响颅底团队的发展。

收集了2006年至2020年在南澳大利亚州接受垂体手术的所有患者的病历。作者团队治疗的所有患者均被纳入。

总共对428例垂体腺瘤进行了手术治疗。总体而言,249例患者中有182例(70%)实现了完全切除,随访期间无复发,49例患者(19%)有残留,但观察到无需治疗。因此,2006年至2020年间,89%的患者垂体手术后无需任何进一步治疗。在检查142例功能性腺瘤患者时,112例(79%)患者术后激素功能障碍无复发,其余30例(21%)患者需要进一步治疗。

我们已经证明,当通过协调努力将这些病例集中在一小群经过专科培训的外科医生手中,而不是采用更通才的方法时,在多家医院的低至中等手术量情况下也能取得可接受的结果。

相似文献

1
The Evolution of Pituitary Surgery in an Australian Health Care Framework.澳大利亚医疗保健框架下垂体手术的发展历程
J Neurol Surg B Skull Base. 2024 Apr 15;86(2):221-228. doi: 10.1055/s-0044-1786044. eCollection 2025 Apr.
8
Endoscopic endonasal transsphenoidal surgery: a mentoring surgical model.鼻内镜经蝶窦手术:一种带教手术模式。
ANZ J Surg. 2012 Jun;82(6):452-6. doi: 10.1111/j.1445-2197.2012.06084.x. Epub 2012 May 9.

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