Zhao Taoqian, Liang Steven H
Department of Radiology and Imaging Sciences, Emory University, Atlanta, Georgia 30322, United States.
ACS Med Chem Lett. 2025 Jan 27;16(3):361-362. doi: 10.1021/acsmedchemlett.5c00012. eCollection 2025 Mar 13.
The present invention relates to novel pyrimidinyl sulfonamide derivatives represented by formula I. These compounds are specifically designed to bind to and modulate GPR17 activities, making them particularly promising for treating diseases associated with GPR17 antagonism.
本发明涉及由式I表示的新型嘧啶基磺酰胺衍生物。这些化合物经过专门设计，可与GPR17结合并调节其活性，使其在治疗与GPR17拮抗作用相关的疾病方面具有特别的前景。
