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[儿童和青少年特应性皮炎与银屑病的全身治疗]

[Systemic therapy of atopic dermatitis and psoriasis in children and adolescents].

作者信息

Sticherling Michael

机构信息

Deutsches Zentrum Immuntherapie, Hautklinik Universitätsklinikum Erlangen, Ulmenweg 18, 91054, Erlangen, Deutschland.

出版信息

Dermatologie (Heidelb). 2025 Apr;76(4):202-210. doi: 10.1007/s00105-025-05486-0. Epub 2025 Mar 19.

Abstract

Psoriasis and atopic dermatitis are among the most frequent chronic, inflammatory skin diseases of childhood and adolescence. Regarding profound consequences for the physical and psychosocial development of affected patients, a timely and individually adapted therapy has to be initiated, in case of severe disease systemic treatment. Modern, targeted, highly efficient and well-tolerated agents are currently available. Overlapping psoriasis and atopic dermatitis have been appreciated recently, both idiopathic and therapeutically induced. Their prevention or early detection is mandatory for optimal management of patients.

摘要

银屑病和特应性皮炎是儿童和青少年时期最常见的慢性炎症性皮肤病。鉴于其对受影响患者的身体和心理社会发育有深远影响,对于重症患者,必须及时启动个体化的适应性治疗,采用全身治疗。目前已有现代、靶向、高效且耐受性良好的药物。重叠性银屑病和特应性皮炎近来已受到关注,包括特发性的以及治疗引起的。对其进行预防或早期检测对于患者的最佳管理至关重要。

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