探索对疫苗安全性的认知：一项关于不同新冠疫苗制剂的意大利全国性调查。

Exploring perceptions of vaccine safety: an Italian national survey on different COVID-19 vaccine formulations.

作者信息

Boccalini Sara, Cosma Claudia, Monaci Pietro, Guida Andrea, Velpini Beatrice, Cerini Gabriele, Chiesi Fabrizio, Bonanni Paolo, Bechini Angela

机构信息

Dipartimento di Scienze della Salute, Università degli Studi di Firenze, Florence, Italy.

Scuola di Specializzazione in Igiene e Medicina Preventiva, Università degli Studi di Firenze, Florence, Italy.

出版信息

Ann Ist Super Sanita. 2025 Jan-Mar;61(1):20-29. doi: 10.4415/ANN_25_01_04.

DOI:10.4415/ANN_25_01_04

PMID:40106319

Abstract

OBJECTIVES

COVID-19 vaccines have proven effective and safe, enabling the resumption of normal life. However, misinformation has hindered vaccination efforts. This study aimed to investigate perceptions of vaccine safety among Italians through an anonymous online survey.

STUDY DESIGN

An anonymous online survey was conducted from April to July 2022 and disseminated through social platforms, among adult individuals living in Italy.

RESULTS

A total of 1,329 individuals participated. Younger individuals and healthcare professionals showed greater trust in vaccines. Education level was significantly associated with perceived vaccine safety. Most respondents, including many healthcare workers and highly educated individuals, believed vaccines to be safe, with confidence levels of 39.5% for mRNA, 32.9% for viral vector, and 39% for protein subunit vaccines. Younger age and trust in institutions were linked to higher confidence in all vaccine types.

CONCLUSIONS

These findings may be useful to further investigate the drivers of vaccine safety perceptions and their relationship with vaccine hesitancy and may help to develop more effective communication campaigns in the future.

摘要

目的

新冠疫苗已被证明有效且安全，使正常生活得以恢复。然而，错误信息阻碍了疫苗接种工作。本研究旨在通过一项匿名在线调查，探究意大利人对疫苗安全性的看法。

研究设计

2022年4月至7月开展了一项匿名在线调查，并通过社交平台在居住于意大利的成年人中进行传播。

结果

共有1329人参与。较年轻的个体和医疗保健专业人员对疫苗表现出更高的信任度。教育水平与对疫苗安全性的认知显著相关。大多数受访者，包括许多医护人员和受过高等教育的个体，认为疫苗是安全的，对信使核糖核酸（mRNA）疫苗的信任度为39.5%，对病毒载体疫苗的信任度为32.9%，对蛋白质亚单位疫苗的信任度为39%。较年轻的年龄以及对机构的信任与对所有疫苗类型的更高信任度相关。