Kamani Yash, Peigh Graham, Verma Nishant, Wasserlauf Jeremiah
Division of Cardiology, Northwestern University, Feinberg School of Medicine, Arthur J. Rubloff Building, 420 East Superior Street, Chicago, IL 60611, USA.
Division of Cardiac Electrophysiology, Northwestern Memorial Hospital, 251 East Huron Street Suite 8-300, Chicago, IL 60611, USA.
Heart Fail Clin. 2025 Apr;21(2):309-326. doi: 10.1016/j.hfc.2024.12.009. Epub 2025 Feb 7.
This review discusses the range of device therapy for ischemic cardiomyopathy (ICM). This article will review the primary data supporting guideline indications for cardiac implantable electronic devices in patients with ICM, with a focus on primary/secondary prevention transvenous implantable cardioverter defibrillators (ICDs), cardiac resynchronization therapy, and subcutaneous/extravascular ICDs. In addition, this review discusses emerging device therapy for ICM including left bundle area pacing/defibrillation, cardiac contractility modulation and baroflex activation therapy. Device therapy for ICM continues to evolve to incorporate diverse modalities across the spectrum from prevention of sudden cardiac death to modifying cardiac remodeling and recovery.
本综述讨论了缺血性心肌病(ICM)的器械治疗范围。本文将回顾支持ICM患者心脏植入式电子设备指南适应证的主要数据,重点关注一级/二级预防经静脉植入式心律转复除颤器(ICD)、心脏再同步治疗以及皮下/血管外ICD。此外,本综述还讨论了ICM的新兴器械治疗,包括左束支区域起搏/除颤、心脏收缩力调制和压力反射激活疗法。ICM的器械治疗不断发展,涵盖了从预防心源性猝死到改善心脏重塑和恢复的各种模式。