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探索广泛性焦虑症症状:来自伊朗一项基于人群研究的关键见解。

Exploring generalized anxiety disorder symptoms: key insights from a population-based study in Iran.

作者信息

Alipour Fardin, Rafiey Hassan, Sarmadi Sahar, DostKaramooz Narges, Mardani Mostafa, Gholamy Golafrooz, Noroozi Mehdi

机构信息

Social Determinants of Health Research Center, Social Health Research Institute, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.

Research Center of Social Welfare Management, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.

出版信息

BMC Psychiatry. 2025 Mar 19;25(1):262. doi: 10.1186/s12888-025-06707-5.

Abstract

AIM

Generalized Anxiety Disorder (GAD) is a common mental health condition with considerable impacts on both individuals and society, associated with high healthcare costs and reduced quality of life. Linked to a range of genetic, psychological, and social factors, GAD also frequently coexists with other mental health conditions. This study investigates the socio-demographic, environmental, and psychosocial risk factors for GAD symptoms in an urban Iranian population, addressing a key research gap and guiding targeted interventions.

METHOD

A cross-sectional study was conducted to determine the prevalence and associated factors of GAD symptoms among adults in Tehran. Using multi-stage sampling, participants completed questionnaires on socio-demographic characteristics, recent stressors, and DSM-5 criteria for GAD. Descriptive statistics identified prevalence patterns, and logistic regression models evaluated associations and adjusted for confounders (p < 0.05). Analyses were conducted in STATA v.14, with adjusted odds ratios and 95% confidence intervals reported.

RESULTS

Of 970 participants, 26% met criteria for GAD (CI 95%: 22%-32%). Individuals with GAD were more likely to be single, dissatisfied with life, of low socioeconomic status, and to report non-healthy status and recent stressors. In multivariable regression, significant risk factors for GAD included female gender (AOR = 1.4, p < 0.01), experiencing at least one recent stressful event (AOR = 1.9, p = 0.01), and poor health status (AOR = 2.8, p < 0.05).

CONCLUSION

This study highlights the prevalence of GAD symptoms in Tehran and underscores the critical roles of policymakers and healthcare providers in addressing it. Effective management requires a multifaceted approach, including individual treatment, social integration, and community support. Future research should focus on culturally sensitive interventions and awareness campaigns to reduce stigma. Overall, the study enriches the literature on GAD in Iran and encourages collaborative efforts to enhance mental health outcomes and community well-being.

摘要

目的

广泛性焦虑障碍(GAD)是一种常见的心理健康状况,对个人和社会都有相当大的影响,与高昂的医疗成本和生活质量下降相关。GAD与一系列遗传、心理和社会因素有关,还经常与其他心理健康状况共存。本研究调查了伊朗城市人口中GAD症状的社会人口学、环境和心理社会风险因素,填补了一个关键的研究空白,并为有针对性的干预措施提供指导。

方法

进行了一项横断面研究,以确定德黑兰成年人中GAD症状的患病率及相关因素。采用多阶段抽样,参与者完成了关于社会人口学特征、近期压力源以及GAD的DSM-5标准的问卷调查。描述性统计确定了患病率模式,逻辑回归模型评估了关联并对混杂因素进行了调整(p < 0.05)。分析在STATA v.14中进行,报告了调整后的优势比和95%置信区间。

结果

在970名参与者中,26%符合GAD标准(95%CI:22%-32%)。患有GAD的个体更有可能单身、对生活不满意、社会经济地位低,并且报告健康状况不佳和近期有压力源。在多变量回归中,GAD的显著风险因素包括女性(AOR = 1.4,p < 0.01)、近期经历至少一次压力事件(AOR = 1.9,p = 0.01)以及健康状况不佳(AOR = 2.8,p < 0.05)。

结论

本研究突出了德黑兰GAD症状的患病率,并强调了政策制定者和医疗服务提供者在应对该问题中的关键作用。有效的管理需要多方面的方法,包括个体治疗、社会融合和社区支持。未来的研究应侧重于文化敏感的干预措施和提高认识的活动,以减少耻辱感。总体而言,该研究丰富了伊朗关于GAD的文献,并鼓励开展合作努力以改善心理健康结果和社区福祉。

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