Zhang Weihua, Han Kezhen, Shao Li, Yang Chao, Zhao Kexin, Jiang Zhao
( 712082) Plateau Biomedical Big Data Mining and Bioinformatics Analysis Laboratory, Xizang Minzu University, Xianyang 712082, China.
( 712082) Key Laboratory for Molecular Genetic Mechanisms and Intervention Research on High Altitude Disease of Xizang Autonomous Region, Xizang Minzu University, Xianyang 712082, China.
Sichuan Da Xue Xue Bao Yi Xue Ban. 2025 Jan 20;56(1):254-261. doi: 10.12182/20250160509.
To investigate the correlation between changes in physiological indicators and altitude, age, and sex among ethnic Tibetan college students living in Xizang on long-term basis upon their first ever visit to a low-altitude region, thereby providing health guidance for long-term residents of high-altitude regions when they visit low-altitude environments for the first time.
A cluster random sampling method was used to select 170 healthy first-year college students of Tibetan ethnicity (85 males and 85 females), from Xizang Minzu University. The participants did not have any respiratory, circulatory, or nervous system diseases, nor any family history of such conditions. Based on their responses to questionnaires and the monitoring data of their physiological indicators, an analysis was conducted to assess the incidence and duration of deacclimatization symptoms among these Tibetan college students during the first month after their arrival at a low-altitude region. In addition, the R programming language and the SPSS software were used to analyze the correlation between changes in blood pressure, heart rate, and body weight and the participants' age, sex, and the altitude of their long-term residence in Xizang before and after their arrival at a low-altitude region.
Statistical analysis revealed that Tibetan college students experienced deacclimatization symptoms within the first week of their first ever visit to a low-altitude region, primarily characterized by dizziness, fatigue, and drowsiness. The incidence was 41.9% among female students and 22.5% among male students. Furthermore, after arriving at low-altitude region, the participants experience an initial decrease followed by a recovery in both blood pressure and heart rate. They gained an average of 1.5 kg in body mass compared with their initial measurements upon arrival in a low-altitude region. Significant differences in blood pressure, heart rate, and body mass were observed among Tibetan students of different sexes and altitudes of their long-term residence in Xizang after their arrival in a low-altitude region.
After arriving at a low-altitude region, Tibetan college students exhibit marked changes in physiological indicators, showing strong correlations between systolic blood pressure, body mass, etc., and sex, altitude, and other parameters.
探讨长期居住在西藏的藏族大学生首次前往低海拔地区时生理指标变化与海拔、年龄和性别的相关性,为高海拔地区长期居住者首次前往低海拔环境时提供健康指导。
采用整群随机抽样方法,从西藏民族大学选取170名健康的藏族大一学生(男85名,女85名)。参与者无任何呼吸、循环或神经系统疾病,也无此类疾病家族史。根据他们对问卷的回答和生理指标监测数据,分析这些藏族大学生到达低海拔地区后第一个月内脱适应症状的发生率和持续时间。此外,使用R编程语言和SPSS软件分析到达低海拔地区前后血压、心率和体重变化与参与者年龄、性别以及他们在西藏长期居住海拔的相关性。
统计分析显示,藏族大学生首次前往低海拔地区的第一周内出现脱适应症状,主要表现为头晕、疲劳和嗜睡。女生发生率为41.9%,男生为22.5%。此外,到达低海拔地区后,参与者的血压和心率先下降后恢复。与刚到达低海拔地区时的初始测量值相比,体重平均增加了1.5千克。到达低海拔地区后,不同性别和长期居住在西藏海拔不同的藏族学生在血压、心率和体重方面存在显著差异。
到达低海拔地区后,藏族大学生生理指标出现明显变化,收缩压、体重等与性别、海拔等参数之间存在较强相关性。