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发作性紧张症、高血压和心动过速:血浆儿茶酚胺升高。

Episodic catatonia, hypertension, and tachycardia: elevated plasma catecholamines.

作者信息

Wheeler A H, Ziegler M G, Insel P A, Motulsky H J

出版信息

Neurology. 1985 Jul;35(7):1053-5. doi: 10.1212/wnl.35.7.1053.

DOI:10.1212/wnl.35.7.1053
PMID:4010946
Abstract

We studied autonomic function in a 34-year-old woman who had episodes of catatonia, hypertension, and tachycardia. In one of these episodes, epinephrine and norepinephrine levels were extremely high. Catecholamine clearance was normal. Platelet alpha 2-adrenergic receptors were normal in number and affinity. Results of the phenylephrine infusion test suggested that these episodes were due to central activation of the sympathetic nervous system.

摘要

我们对一名34岁患有紧张症、高血压和心动过速发作的女性进行了自主神经功能研究。在其中一次发作中,肾上腺素和去甲肾上腺素水平极高。儿茶酚胺清除率正常。血小板α2 - 肾上腺素能受体数量和亲和力正常。去氧肾上腺素输注试验结果表明,这些发作是由于交感神经系统的中枢激活所致。

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Episodic catatonia, hypertension, and tachycardia: elevated plasma catecholamines.发作性紧张症、高血压和心动过速:血浆儿茶酚胺升高。
Neurology. 1985 Jul;35(7):1053-5. doi: 10.1212/wnl.35.7.1053.
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Plasma catecholamines and essential hypertension. An analytical review.血浆儿茶酚胺与原发性高血压。一项分析性综述。
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Variations in circulating catecholamines fail to alter human platelet alpha-2-adrenergic receptor number or affinity for [3H]yohimbine or [3H]dihydroergocryptine.循环儿茶酚胺的变化未能改变人血小板α-2-肾上腺素能受体的数量或对[3H]育亨宾或[3H]二氢麦角隐亭的亲和力。
J Clin Invest. 1984 Sep;74(3):1063-72. doi: 10.1172/JCI111473.
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Norepinephrine transporter-deficient mice exhibit excessive tachycardia and elevated blood pressure with wakefulness and activity.去甲肾上腺素转运体缺陷小鼠在清醒和活动时表现出过度心动过速和血压升高。
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[Effect of street noise on blood catecholamines, cyclic AMP and various cardiovascular and metabolic functions in a group of subjects with untreated essential hypertension].[街道噪音对一组未经治疗的原发性高血压患者血液儿茶酚胺、环磷酸腺苷及各种心血管和代谢功能的影响]
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Decreased platelet-free dopamine and unchanged noradrenaline and adrenaline in essential hypertension.原发性高血压患者中游离血小板多巴胺水平降低,去甲肾上腺素和肾上腺素水平无变化。
Thromb Haemost. 1988 Oct 31;60(2):251-4.

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