Drysdale David R, Gartner Mark E, Smith Ryan A, Atoa Bradley J, Fleetwood Aaron D, Sjulin Tyson J, Osswald Michael B
Department of Medicine, Division of Internal Medicine, Brooke Army Medical Center, San Antonio, USA.
Department of Medicine, Division of Pulmonary and Critical Care Medicine, Brooke Army Medical Center, San Antonio, USA.
Cureus. 2025 Feb 17;17(2):e79144. doi: 10.7759/cureus.79144. eCollection 2025 Feb.
Bing-Neel syndrome (BNS) is a rare complication of Waldenström macroglobulinemia, characterized by lymphoplasmacytic lymphoma infiltration of the CNS. We present a pathologically confirmed case of BNS in a patient who was initially misdiagnosed with COVID-19 pneumonia and critical illness polyneuropathy. This case underscores the diagnostic challenges associated with BNS and highlights the importance of early recognition.
宾-尼尔综合征(BNS)是华氏巨球蛋白血症的一种罕见并发症,其特征为中枢神经系统受淋巴浆细胞淋巴瘤浸润。我们报告一例经病理证实的BNS病例,该患者最初被误诊为新冠肺炎肺炎和危重症多神经病。该病例强调了与BNS相关的诊断挑战,并突出了早期识别的重要性。