Kota Nikhil, Keshireddy Anusha, Pruthi Anika, Abidin Zain, Koneru Manisha
Neurosciences, Cooper Medical School of Rowan University, Camden, USA.
Neurointerventional Surgery, Cooper University Health Care, Camden, USA.
Cureus. 2025 Feb 17;17(2):e79163. doi: 10.7759/cureus.79163. eCollection 2025 Feb.
Chronic subdural hematoma (cSDH) is the accumulation of blood in the subdural space, primarily affecting older adults. Radiomics is a rapidly emerging field that integrates artificial intelligence (AI) with imaging to improve diagnostic precision and prognostic predictions, including hematoma expansion and recurrence. However, the heterogeneous study designs, endpoints, and reporting standards limit its clinical application. This scoping review queried PubMed for studies published before or on December 25, 2024, using terms related to cSDH and AI-based imaging analysis. Inclusion criteria required primary research applying AI to cSDH imaging and reporting prognostic endpoints such as recurrence, expansion, or treatment response. Extracted data included methodological variables, imaging modalities, endpoints of interest, and performance metrics. Most studies used computed tomography (CT) imaging for analysis, with hematoma recurrence being the most frequently evaluated endpoint of interest. However, there was wide inconsistency in the reporting of model performance metrics. Thus, radiomics offers opportunities to improve outcome prediction and treatment planning in cSDH. Future work should focus on defining clinically meaningful endpoints, standardizing metrics, and validating models prospectively to facilitate integration into practice.
慢性硬膜下血肿(cSDH)是指血液在硬膜下腔积聚,主要影响老年人。放射组学是一个迅速兴起的领域,它将人工智能(AI)与影像学相结合,以提高诊断精度和预后预测能力,包括血肿扩大和复发情况。然而,研究设计、终点指标和报告标准的异质性限制了其临床应用。本范围综述在PubMed数据库中检索了截至2024年12月25日发表的、使用与cSDH和基于AI的影像分析相关术语的研究。纳入标准要求是将AI应用于cSDH影像并报告诸如复发、扩大或治疗反应等预后终点指标的原发性研究。提取的数据包括方法学变量、影像模态、感兴趣的终点指标和性能指标。大多数研究使用计算机断层扫描(CT)影像进行分析,血肿复发是最常评估的感兴趣终点指标。然而,模型性能指标的报告存在很大差异。因此,放射组学为改善cSDH的预后预测和治疗规划提供了机会。未来的工作应聚焦于定义具有临床意义的终点指标、规范指标以及前瞻性验证模型,以促进其融入临床实践。