• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

放疗导致的鼻咽部纤维化致气道困难:一例报告

Radiation-Induced Nasopharyngeal Fibrosis Resulting in a Difficult Airway: A Case Report.

作者信息

Akazawa Mai, Shimizu Morihiro, Fujino Yoshihisa, Kato Hiromi

机构信息

Department of Comprehensive Surgery, Shiga University of Medical Science, Shiga, JPN.

Department of Anaesthesiology, Shiga University of Medical Science, Shiga, JPN.

出版信息

Cureus. 2025 Feb 16;17(2):e79130. doi: 10.7759/cureus.79130. eCollection 2025 Feb.

DOI:10.7759/cureus.79130
PMID:40109800
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11920768/
Abstract

Patients with head and neck cancer often experience airway complications. This case highlights a patient with nasopharyngeal cancer post-radiotherapy (RT), who presented with a difficult airway (DA). An 83-year-old woman, scheduled for a partial left lower lobe pneumonectomy, had received RT for nasopharyngeal cancer one year prior. Physical examination revealed trismus, limited neck movement, Mallampati class IV, and grade III on the upper lip bite test. Bronchoscopy showed mucous membrane irregularities in the nasopharynx, along with an edematous epiglottis and vocal cords. After general anesthesia induction, both mask ventilation and McGrath™ intubation (Covidien Inc., Tokyo, Japan) attempts failed. Lifting the patient's tongue manually allowed visualization of the vocal cords via a fiberoptic bronchoscope, enabling successful intubation. Patients who have undergone head and neck radiotherapy (HNRT) are at increased risk of DAs due to radiation-induced fibrosis (RIF) of pharyngeal soft tissues.

摘要

头颈癌患者常出现气道并发症。本病例突出了一名鼻咽癌放疗后患者,该患者出现了困难气道(DA)。一名83岁女性计划行左下肺叶部分切除术,一年前曾接受鼻咽癌放疗。体格检查发现牙关紧闭、颈部活动受限、Mallampati分级为IV级,上唇咬试验为III级。支气管镜检查显示鼻咽部黏膜不规则,会厌和声带有水肿。全身麻醉诱导后,面罩通气和使用麦格拉斯™喉镜(柯惠医疗公司,东京,日本)插管尝试均失败。手动抬起患者舌头后,通过纤维支气管镜可看到声带,从而成功插管。由于咽部软组织的放射性纤维化(RIF),接受过头颈放疗(HNRT)的患者发生困难气道的风险增加。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/417d/11920768/d43094c05ac3/cureus-0017-00000079130-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/417d/11920768/286ccf43afbf/cureus-0017-00000079130-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/417d/11920768/d43094c05ac3/cureus-0017-00000079130-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/417d/11920768/286ccf43afbf/cureus-0017-00000079130-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/417d/11920768/d43094c05ac3/cureus-0017-00000079130-i02.jpg

相似文献

1
Radiation-Induced Nasopharyngeal Fibrosis Resulting in a Difficult Airway: A Case Report.放疗导致的鼻咽部纤维化致气道困难:一例报告
Cureus. 2025 Feb 16;17(2):e79130. doi: 10.7759/cureus.79130. eCollection 2025 Feb.
2
Air-Q laryngeal airway for rescue and tracheal intubation.用于急救和气管插管的Air-Q喉罩气道
J Clin Anesth. 2016 Aug;32:108-11. doi: 10.1016/j.jclinane.2016.02.004. Epub 2016 Apr 20.
3
Airway physical examination tests for detection of difficult airway management in apparently normal adult patients.气道体格检查用于检测表面上正常的成年患者的困难气道管理情况。
Cochrane Database Syst Rev. 2018 May 15;5(5):CD008874. doi: 10.1002/14651858.CD008874.pub2.
4
A data review of airway management in patients with oral cavity or oropharyngeal cancer: a single-institution experience.口腔或口咽癌患者气道管理的数据回顾:单机构经验。
BMC Anesthesiol. 2019 Jun 1;19(1):92. doi: 10.1186/s12871-019-0770-2.
5
[Tracheal intubation with Pentax AWS Airway Scope after failed fiberoptic intubation and failed insertion of the intubating laryngeal mask airway].[在纤维支气管镜引导插管失败和插入喉罩气道插管失败后使用宾得AWS气道镜进行气管插管]
Masui. 2010 Apr;59(4):470-2.
6
Unilateral vocal cord palsy occurred after difficult endotracheal intubation using intubating laryngeal mask airway: A case report.使用插管喉罩气道进行困难气管插管后发生单侧声带麻痹:一例报告。
Korean J Anesthesiol. 2009 Feb;56(2):200-203. doi: 10.4097/kjae.2009.56.2.200.
7
[Efficacy of a Bronchofiberscope in Combination with the GlideScopee in a Difficult Airway Patient].[纤维支气管镜与GlideScope喉镜联合用于困难气道患者的疗效]
Masui. 2016 Oct;65(10):1013-1015.
8
[Tracheal intubation in patients with Williams syndrome].[威廉姆斯综合征患者的气管插管]
Masui. 2010 May;59(5):632-4.
9
Blind nasal intubation as an alternative to difficult intubation approaches.盲探鼻腔插管作为困难插管方法的替代方案。
J Dent Anesth Pain Med. 2015 Sep;15(3):181-184. doi: 10.17245/jdapm.2015.15.3.181. Epub 2015 Sep 30.
10
The intubating laryngeal mask airway in failed fibreoptic intubation.纤维光导喉镜插管失败时的气管插管型喉罩气道
Can J Anaesth. 1999 Apr;46(4):376-8. doi: 10.1007/BF03013232.

本文引用的文献

1
In Reference to Difficult Tracheal Intubation and Airway Outcomes After Radiation for Nasopharyngeal Carcinoma.关于鼻咽癌放疗后的困难气管插管及气道结局
Laryngoscope. 2023 Dec;133(12):E67. doi: 10.1002/lary.30948. Epub 2023 Aug 9.
2
Difficult Tracheal Intubation and Airway Outcomes after Radiation for Nasopharyngeal Carcinoma.鼻咽癌放疗后困难气管插管和气道结果。
Laryngoscope. 2024 Jan;134(1):120-126. doi: 10.1002/lary.30767. Epub 2023 May 30.
3
Post-radiotherapy suggests a possible difficult airway even with an asymptomatic supraglottic change.
放疗后提示即使声门上改变无症状也可能存在困难气道。
JA Clin Rep. 2022 Dec 29;8(1):102. doi: 10.1186/s40981-022-00592-7.
4
The impact of head and neck radiation on airway management: a retrospective data review.头颈部放疗对气道管理的影响:一项回顾性数据综述。
Can J Anaesth. 2022 Dec;69(12):1562-1564. doi: 10.1007/s12630-022-02331-z. Epub 2022 Oct 21.
5
Radiation-Induced Fibrosis in Patients with Head and Neck Cancer: A Review of Pathogenesis and Clinical Outcomes.头颈部癌患者的放射性纤维化:发病机制与临床结果综述
Clin Med Insights Oncol. 2022 Jan 30;16:11795549211036898. doi: 10.1177/11795549211036898. eCollection 2022.
6
2022 American Society of Anesthesiologists Practice Guidelines for Management of the Difficult Airway.2022 年美国麻醉医师学会困难气道管理实践指南。
Anesthesiology. 2022 Jan 1;136(1):31-81. doi: 10.1097/ALN.0000000000004002.
7
Dose to swallowing structures and dysphagia in head and neck Intensity Modulated Radiation Therapy - A long term prospective analysis.头颈部调强放射治疗中吞咽结构的剂量与吞咽困难——一项长期前瞻性分析。
Rep Pract Oncol Radiother. 2019 Nov-Dec;24(6):654-659. doi: 10.1016/j.rpor.2019.09.012. Epub 2019 Nov 1.
8
Radiation-induced fibrosis: mechanisms and implications for therapy.辐射诱导的纤维化:机制及其对治疗的影响
J Cancer Res Clin Oncol. 2015 Nov;141(11):1985-94. doi: 10.1007/s00432-015-1974-6. Epub 2015 Apr 25.
9
Incidence, predictors, and outcome of difficult mask ventilation combined with difficult laryngoscopy: a report from the multicenter perioperative outcomes group.困难面罩通气合并困难喉镜显露的发生率、预测因素和结局:多中心围术期结局研究组的报告。
Anesthesiology. 2013 Dec;119(6):1360-9. doi: 10.1097/ALN.0000435832.39353.20.
10
Prediction and outcomes of impossible mask ventilation: a review of 50,000 anesthetics.面罩通气困难的预测与结果:50000例麻醉回顾
Anesthesiology. 2009 Apr;110(4):891-7. doi: 10.1097/ALN.0b013e31819b5b87.