* Assistant Professor, ‡ Lead Statistician, § Resident, ‖ Research Fellow, ** Clinical Instructor, ‖‖ Software Analyst, ## Professor and Chairman, Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, Michigan. † Associate Professor, Department of Anesthesiology and Perioperative Medicine, Oregon Health and Science University, Portland, Oregon. # Acting Assistant Professor, Department of Anesthesiology, Seattle Children's Hospital, University of Washington School of Medicine, Seattle, Washington. †† Associate Professor and Chairman, Department of Anesthesiology, University of Tennessee Graduate School of Medicine, Knoxville, Tennessee. ‡‡ Assistant Professor, §§ Associate Professor and Vice Chair, Department of Anesthesiology, University of Colorado, Aurora, Colorado. *** The members of the Multicenter Perioperative Outcomes Group (MPOG) Perioperative Clinical Research Committee are included in the appendix.
Anesthesiology. 2013 Dec;119(6):1360-9. doi: 10.1097/ALN.0000435832.39353.20.
Research regarding difficult mask ventilation (DMV) combined with difficult laryngoscopy (DL) is extremely limited even though each technique serves as a rescue for one another.
Four tertiary care centers participating in the Multicenter Perioperative Outcomes Group used a consistent structured patient history and airway examination and airway outcome definition. DMV was defined as grade 3 or 4 mask ventilation, and DL was defined as grade 3 or 4 laryngoscopic view or four or more intubation attempts. The primary outcome was DMV combined with DL. Patients with the primary outcome were compared to those without the primary outcome to identify predictors of DMV combined with DL using a non-parsimonious logistic regression.
Of 492,239 cases performed at four institutions among adult patients, 176,679 included a documented face mask ventilation and laryngoscopy attempt. Six hundred ninety-eight patients experienced the primary outcome, an overall incidence of 0.40%. One patient required an emergent cricothyrotomy, 177 were intubated using direct laryngoscopy, 284 using direct laryngoscopy with bougie introducer, 163 using videolaryngoscopy, and 73 using other techniques. Independent predictors of the primary outcome included age 46 yr or more, body mass index 30 or more, male sex, Mallampati III or IV, neck mass or radiation, limited thyromental distance, sleep apnea, presence of teeth, beard, thick neck, limited cervical spine mobility, and limited jaw protrusion (c-statistic 0.84 [95% CI, 0.82-0.87]).
DMV combined with DL is an infrequent but not rare phenomenon. Most patients can be managed with the use of direct or videolaryngoscopy. An easy to use unweighted risk scale has robust discriminating capacity.
尽管每种技术都互为彼此的抢救措施,但对于困难面罩通气(DMV)与困难喉镜检查(DL)相结合的研究极为有限。
四个参与多中心围手术期结局组的三级护理中心使用一致的结构化患者病史和气道检查以及气道结局定义。DMV 定义为 3 级或 4 级面罩通气,DL 定义为 3 级或 4 级喉镜视图或 4 次以上插管尝试。主要结局是 DMV 与 DL 相结合。通过非简约逻辑回归,将具有主要结局的患者与没有主要结局的患者进行比较,以确定 DMV 与 DL 相结合的预测因素。
在四个机构的成年患者中进行的 492239 例手术中,有 176679 例记录了面罩通气和喉镜检查尝试。698 例患者出现主要结局,总体发生率为 0.40%。1 例患者需要紧急环甲膜切开术,177 例患者经直接喉镜插管,284 例患者经直接喉镜加引导管插管,163 例患者经视频喉镜插管,73 例患者经其他技术插管。主要结局的独立预测因素包括年龄 46 岁或以上、体重指数 30 或以上、男性、Mallampati III 或 IV 级、颈部肿块或放疗、有限的甲状软骨上距离、睡眠呼吸暂停、存在牙齿、胡须、粗颈、有限的颈椎活动度和有限的下颌突出(C 统计量 0.84[95%CI,0.82-0.87])。
DMV 与 DL 相结合是一种罕见但并不罕见的现象。大多数患者可以通过使用直接喉镜或视频喉镜进行管理。一个易于使用的无权重风险评分具有强大的判别能力。