Wang Yi-Bing, Chen Xin-Xia, Li Song-Tao, Yan Hong-Ping
Department of Psychiatry, Shaoxing 7th People's Hospital, Shaoxing 312000, Zhejiang Province, China.
World J Psychiatry. 2025 Mar 19;15(3):101190. doi: 10.5498/wjp.v15.i3.101190.
Depression is a prevalent mental health disorder with significant impacts on individuals and families. We hypothesize that combining family cognitive therapy (FCT) with pharmacotherapy will be more effective in managing depression and improving family dynamics than pharmacotherapy alone.
To investigate the effects of FCT combined with sertraline on depression, aggressive behavior, and family functioning in patients with major depressive disorder (MDD).
This study involved 178 patients diagnosed with MDD at the Shaoxing 7th People's Hospital from January 2022 to April 2024. Patients were divided into two groups according to whether they received FCT. FCT included both patient-focused cognitive therapy and family-focused psychological guidance over a 12-week period.
The observation group receiving combined treatment showed significantly greater reductions in depressive symptoms (Beck Depression Inventory scores: 27.4 ± 4.7 to 18.6 ± 5.2) compared to the control group (28.1 ± 5.5 to 20.9 ± 4.9), with = 0.031 for the difference between groups. Improvements in family functioning and marital quality were also observed, with < 0.001 for key dimensions on the Family Assessment Device and Enrich Marital Scale.
The combination of FCT with sertraline effectively reduces depressive symptoms and improves family dynamics in patients with MDD.
抑郁症是一种常见的心理健康障碍,对个人和家庭有重大影响。我们假设,将家庭认知疗法(FCT)与药物治疗相结合,在治疗抑郁症和改善家庭关系方面比单纯药物治疗更有效。
探讨FCT联合舍曲林对重度抑郁症(MDD)患者的抑郁、攻击行为及家庭功能的影响。
本研究纳入了2022年1月至2024年4月在绍兴市第七人民医院诊断为MDD的178例患者。根据是否接受FCT将患者分为两组。FCT包括为期12周的以患者为中心的认知疗法和以家庭为中心的心理指导。
与对照组(贝克抑郁量表评分:28.1±5.5降至20.9±4.9)相比,接受联合治疗的观察组抑郁症状显著减轻(贝克抑郁量表评分:27.4±4.7降至18.6±5.2),组间差异P = 0.031。家庭功能和婚姻质量也有所改善,家庭评估量表和充实婚姻量表关键维度的P < 0.001。
FCT联合舍曲林可有效减轻MDD患者的抑郁症状,改善家庭关系。