Subedi Bhusan Kumar, Homagain Sushan, Ghimire Jeevan, Subedi Shova, Paudel Suruchi, Pandeya Govinda, Jha Saroj Kumar, Shrestha Nishan, Twanabasu Sajal, Devkota Sadina
Dhading Hospital, Nilkantha Municipality, Dhading, Nepal.
Bir Hospital, National Academy of Medical Sciences, Kathmandu Nepal.
Ann Med Surg (Lond). 2025 Jan 7;87(2):460-465. doi: 10.1097/MS9.0000000000002889. eCollection 2025 Feb.
Mad (Wild) honey, used as alternative medicine in some countries where cases of poisoning are reported, got its name due to its intoxicating effects. Poisoning due to mad honey mostly presents as bradycardia and hypotension.
We report 11 cases involving 6 females and 5 males, of mad honey poisoning used for medicinal purposes. All patients were young adults (average age 43.9 years) except for one. Lightheadedness, dizziness and nausea were the most common complaints. All presented in bradycardia ranging from 35 to 60 beats per minute. All cases were managed conservatively while one required vasopressors support. All patients improved with a couple of days of supportive care.
Mad honey poisoning seems to be a geographically restricted entity as the majority of cases are reported from a particular region. Because of its use as an alternative medicine for various purposes, cases of intoxication occur year around. Although the signs and symptoms of mad honey can be life threatening including nausea, dizziness, bradycardia, and hypotension, the prognosis is generally good.
Although the prognosis is fairly good, mad honey intoxication has significant morbidity. Lack of awareness about the potential complications of consuming mad honey seems to be the cause of cases of poisoning seen annually.
疯蜜（野蜂蜜）在一些有中毒病例报告的国家被用作替代药物，因其具有致醉作用而得名。疯蜜中毒主要表现为心动过缓和低血压。
我们报告了11例因药用疯蜜中毒的病例，其中6例为女性，5例为男性。除1例患者外，所有患者均为年轻成年人（平均年龄43.9岁）。最常见的症状是头晕、眩晕和恶心。所有患者均表现为心动过缓，心率每分钟35至60次。所有病例均采用保守治疗，其中1例需要血管升压药支持。经过几天的支持治疗，所有患者均康复。
疯蜜中毒似乎是一种受地域限制的病症，因为大多数病例报告来自特定地区。由于其被用于各种替代药物用途，中毒病例全年都有发生。尽管疯蜜的体征和症状可能危及生命，包括恶心、头晕、心动过缓和低血压，但总体预后良好。
尽管预后相当好，但疯蜜中毒有显著的发病率。对食用疯蜜潜在并发症缺乏认识似乎是每年中毒病例的原因。
