Hartveit F, Tangen M, Halvorsen J F, Samsonsen G
Oncology. 1985;42(4):210-6. doi: 10.1159/000226033.
This paper reports a difference in the lymphoid tissue area in the axilla of node-negative breast cancer patients in the first versus the second half of the year, the area being greater in the latter. This observations is new. It is based on data from 72 patients derived over 25 consecutive months and is in keeping with previous reports of a proliferative histological picture in the nodes at this time. The findings were less marked in the node-positive cases (23), and were not accompanied by an increase in nodal number. No such difference was seen in 80 specimens from noncancer autopsy controls. A total of 1,868 nodes were evaluated. The possibility that light-mediated reactions may be involved is discussed briefly, as is the role of this proliferative reaction and its probable mediation relative to the parallel histological changes reported in primary breast carcinomas at this time.
本文报道了在一年的上半年与下半年，淋巴结阴性乳腺癌患者腋窝淋巴组织面积存在差异，下半年该面积更大。这一观察结果是新的。它基于连续25个月收集的72例患者的数据，与此前关于此时淋巴结增生性组织学表现的报道相符。在淋巴结阳性病例（23例）中，这些发现不太明显，且未伴有淋巴结数量增加。在80例非癌尸检对照标本中未观察到这种差异。共评估了1868个淋巴结。文中简要讨论了光介导反应可能涉及的可能性，以及这种增生反应的作用及其与此时原发性乳腺癌所报道的平行组织学变化的可能关联。
