Rodriguez Amanda, Velasquez Diego, Marquez Leonardo, Ramos Jose Maria, Zambrana Nataly, Masotti Maria, Kripfgans Oliver, Chan Hsun-Liang
Department of Periodontics and Oral Medicine, School of Dentistry, University of Michigan, Ann Arbor, Michigan, United States of America.
Department of Periodontology, University of Illinois Chicago College of Dentistry, Chicago, Illinois, United States of America.
PLoS One. 2025 Mar 20;20(3):e0319271. doi: 10.1371/journal.pone.0319271. eCollection 2025.
The MAPS score was introduced to evaluate the bioMechanical, Aesthetic/Anatomical, Pathophysiologic, and Subject-related parameters for the healing assessment of 20 patients who underwent GBR in the posterior mandible retrospectively. Intraoral photography was taken at 3-, 10-, 21 days, and 5 months, resulting in 80 follow-up visits. Two independent examiners evaluated the photos giving scores for each timepoint and tested against horizontal bone gain (CBCT) for predictability.
Cohen's Kappa values showed high intra- and inter-examiner agreement. Pearson's correlation showed an inverse correlation between baseline bone width and bone changes at a 3 mm level (R2 = 0.23). The higher M, A, and P values at any time point were associated with higher bone gain. The 10-day MAPS score turns out the most predictive of bone gain (RMSE 1.32, R2 0.75). In addition, increasing the average P score by 1 point at 10 days is associated with an increase in bone gain of 1.23 (p=.057).
The MAPS score improves consistently over the 5-month healing period. However, no statistically significant difference is observed between the scores at 21 days and 5 months, reflecting the clinical healing pattern for GBR. The overall MAPS score correlated with bone changes after GBR procedures, indicating its potential for estimating hard tissue regenerative outcomes.
引入MAPS评分以评估20例接受下颌骨后部引导骨再生（GBR）患者愈合情况的生物力学、美学/解剖学、病理生理学和与受试者相关的参数。在术后3天、10天、21天和5个月进行口内摄影，共80次随访。两名独立检查者对照片进行评估，为每个时间点打分，并与水平骨增量（CBCT）进行预测性对比。
Cohen's Kappa值显示检查者内和检查者间具有高度一致性。Pearson相关性分析显示，在3mm水平，基线骨宽度与骨变化呈负相关（R2 = 0.23）。在任何时间点，较高的M、A和P值与较高的骨增量相关。结果显示，10天时的MAPS评分对骨增量的预测性最强（均方根误差1.32，R2 0.75）。此外，10天时平均P评分每增加1分，骨增量增加1.23（p = 0.057）。
在5个月的愈合期内，MAPS评分持续改善。然而，21天和5个月时的评分之间未观察到统计学上的显著差异，这反映了GBR的临床愈合模式。整体MAPS评分与GBR术后的骨变化相关，表明其在估计硬组织再生结果方面的潜力。
