Department of Periodontics and Oral Medicine, School of Dentistry, University of Michigan, Ann Arbor, Michigan, United States of America.
Department of Periodontics, University of Louisville School of Dentistry, Louisville, Kentucky, United States of America.
PLoS One. 2024 Feb 8;19(2):e0290050. doi: 10.1371/journal.pone.0290050. eCollection 2024.
Wound healing monitoring for abnormality identification and intervention is crucial to securing a successful surgical outcome. Indices have been used to summarize the degree of healing. Given the increasing frequency of regenerative procedures which preserve dentition and implant stability, and the higher esthetic demands, an appraisal of the available indices is needed to identify the current knowledge gap. This study aimed to systematically review published oral wound healing indices and scores.
A complete literature electronic search in 5 databases was conducted by two reviewers. A combination of keywords related to oral wound healing was used.
A total of 11 articles were included in the evaluation of various procedures (conventional periodontal procedures, guided tissue regeneration, soft tissue reconstruction procedures, and tooth extractions), at different time points (1 day to 12 weeks), with a focus on diverse clinical signs and symptoms. Frequently evaluated parameters included wound dehiscence/epithelialization (91%), tissue color (redness) (73%), suppuration (55%), swelling/edema (55%), and hemostasis (55%). Other less commonly used parameters include esthetics-related and patient-centered outcomes.
The available indices evaluate a diverse group of subjective clinical signs and symptoms to estimate the underlying biological healing events and assess the degree of clinical success. The majority of the included indices are not validated. Quantitative and objective subclinical parameters including blood perfusion, biomaterial stability, and completeness of epithelialization, are needed for customized wound healing care and better outcome prediction.
监测伤口愈合情况以识别和干预异常对于确保手术成功至关重要。指数被用于总结愈合程度。鉴于再生程序的频率不断增加,这些程序可以保留牙齿和植入物的稳定性,并满足更高的美学要求,因此需要评估现有的指数以确定当前的知识差距。本研究旨在系统地综述已发表的口腔伤口愈合指数和评分。
两名评审员在 5 个数据库中进行了全面的文献电子检索。使用了与口腔伤口愈合相关的关键词组合。
共有 11 篇文章被纳入各种程序(常规牙周程序、引导组织再生、软组织重建程序和拔牙)的评估,时间点不同(1 天至 12 周),重点关注不同的临床体征和症状。经常评估的参数包括伤口裂开/上皮化(91%)、组织颜色(红色)(73%)、化脓(55%)、肿胀/水肿(55%)和止血(55%)。其他较少使用的参数包括与美学相关和以患者为中心的结果。
现有的指数评估了一组多样化的主观临床体征和症状,以估计潜在的生物学愈合事件,并评估临床成功的程度。大多数纳入的指数未经验证。需要定量和客观的亚临床参数,包括血液灌注、生物材料稳定性和上皮化的完整性,以实现定制化的伤口愈合护理和更好的结果预测。