R Jayavarmaa, Das Gaurav
Department of Surgical Oncology, Dr. B. Borooah Cancer Institute, Guwahati, Assam India.
Indian J Surg Oncol. 2025 Feb;16(1):117-121. doi: 10.1007/s13193-024-02051-4. Epub 2024 Aug 3.
Inflammatory linear verrucous epidermal nevus (ILVEN) is a rare type of cutaneous nevus that has female predilection which occurs at birth or infancy and evolves along Blaschko's lines, perceived unilaterally, over the buttocks, legs, and arms. In this case report, ILVEN was associated with multiple ulcero-proliferative skin lesions over the dorsum of the left foot, which on biopsy were proven to be malignant adnexal tumors. A 51-year-old female presented with linear, scaly, and verrucous skin lesions on her left buttock, thigh, and leg unilaterally along Blaschko's lines after birth. Post-operative biopsy taken from the dorsum of the foot reveals trichoepithelioma. Biopsy taken from the back of the thigh and leg reveals inflammatory linear verrucous epidermal nevus. Single-stage surgical resection of both lesions, performed with primary closure of all the areas, except the gluteal region which is closed by V-Y advancement flap. The outcome was satisfactory for the patient after surgical resection and reconstruction. No recurrence was detected during the follow-up visits. ILVEN is an uncommon type of hyperplastic cutaneous disease. ILVEN perchance associated with malignancy. Henceforth, it has to be considered during the evaluation of similar lesions for optimal treatment intervention.
炎症性线状疣状表皮痣（ILVEN）是一种罕见的皮肤痣，女性多见，出生时或婴儿期发病，沿Blaschko线发展，单侧分布于臀部、腿部和手臂。在本病例报告中，ILVEN与左脚背多发溃疡性增殖性皮肤病变相关，活检证实为恶性附属器肿瘤。一名51岁女性出生后左侧臀部、大腿和腿部沿Blaschko线单侧出现线状、鳞屑性和疣状皮肤病变。足部背侧术后活检显示毛发上皮瘤。大腿和腿部后侧活检显示炎症性线状疣状表皮痣。对两个病变进行一期手术切除，除臀区采用V-Y推进皮瓣闭合外，所有区域均进行一期缝合。手术切除和重建后患者预后良好。随访期间未发现复发。ILVEN是一种不常见的增生性皮肤疾病。ILVEN可能与恶性肿瘤相关。因此，在评估类似病变时必须考虑到这一点，以便进行最佳治疗干预。
