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单纯疱疹病毒肺炎作为新冠病毒感染的晚期并发症：一例独特病例报告

Herpes Simplex Virus (HSV) Pneumonitis as a Late Complication of COVID-19 Infection: A Unique Case Report.

作者信息

Pasula Shirisha, Vijayan Rupalakshmi

机构信息

Internal Medicine/Infectious Diseases, University of California, Fresno, USA.

Family Medicine, St. Elizabeth Mercy Boardman Hospital, Boardman, USA.

出版信息

Cureus. 2025 Feb 18;17(2):e79228. doi: 10.7759/cureus.79228. eCollection 2025 Feb.

DOI:10.7759/cureus.79228
PMID:40115679
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11925227/
Abstract

This case report details a patient who presented with gradually worsening shortness of breath and hemoptysis over a year following her COVID-19 infection. Notably, the patient was otherwise immunocompetent. After a comprehensive evaluation, she was diagnosed with herpes simplex virus (HSV) pneumonitis. The patient was treated with oral acyclovir, which is the standard approach for managing HSV pneumonitis. This case highlights the potential for delayed HSV reactivation and the need for awareness of such complications in patients recovering from COVID-19.

摘要

本病例报告详细介绍了一名患者，她在感染新冠病毒一年后出现逐渐加重的呼吸急促和咯血症状。值得注意的是，该患者免疫功能正常。经过全面评估，她被诊断为单纯疱疹病毒性肺炎。患者接受了口服阿昔洛韦治疗，这是治疗单纯疱疹病毒性肺炎的标准方法。本病例突出了单纯疱疹病毒延迟激活的可能性，以及在新冠康复患者中认识此类并发症的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc62/11925227/73062f5dadba/cureus-0017-00000079228-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc62/11925227/a85dfb3d1826/cureus-0017-00000079228-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc62/11925227/e54910764d0b/cureus-0017-00000079228-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc62/11925227/b039dd1fb8d4/cureus-0017-00000079228-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc62/11925227/73062f5dadba/cureus-0017-00000079228-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc62/11925227/a85dfb3d1826/cureus-0017-00000079228-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc62/11925227/e54910764d0b/cureus-0017-00000079228-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc62/11925227/b039dd1fb8d4/cureus-0017-00000079228-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc62/11925227/73062f5dadba/cureus-0017-00000079228-i04.jpg

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本文引用的文献

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Med Clin (Engl Ed). 2023 Jan 20;160(2):66-70. doi: 10.1016/j.medcle.2022.04.019. Epub 2022 Dec 26.
2
A rare case of aseptic herpes simplex virus-1 meningitis in a patient with recent COVID-19.一例近期 COVID-19 患者的无菌性单纯疱疹病毒-1 脑膜炎罕见病例。
Folia Med (Plovdiv). 2022 Feb 28;64(1):148-151. doi: 10.3897/folmed.64.e59677.
3
Post-COVID-19 HSV encephalitis: a review.
新冠病毒感染后单纯疱疹病毒性脑炎：综述。
QJM. 2022 Apr 20;115(4):222-227. doi: 10.1093/qjmed/hcac060.
4
The prevalence of early- and late-onset bacterial, viral, and fungal respiratory superinfections in invasively ventilated COVID-19 patients.COVID-19 患者有创机械通气后早发和晚发细菌、病毒和真菌呼吸道合并感染的发生率。
J Med Virol. 2022 May;94(5):1920-1925. doi: 10.1002/jmv.27548. Epub 2022 Jan 4.
5
HSV-1 reactivation is associated with an increased risk of mortality and pneumonia in critically ill COVID-19 patients.单纯疱疹病毒 1 型（HSV-1）再激活与危重症 COVID-19 患者的死亡率和肺炎风险增加相关。
Crit Care. 2021 Dec 6;25(1):417. doi: 10.1186/s13054-021-03843-8.
6
Herpes simplex virus and cytomegalovirus reactivations among severe COVID-19 patients.重症 COVID-19 患者中单纯疱疹病毒和巨细胞病毒的再激活
Crit Care. 2020 Aug 28;24(1):530. doi: 10.1186/s13054-020-03252-3.
7
Two Fatal Cases of Acute Liver Failure Due to HSV-1 Infection in COVID-19 Patients Following Immunomodulatory Therapies.两例新冠病毒感染患者在接受免疫调节治疗后因单纯疱疹病毒1型感染导致急性肝衰竭的致命病例。
Clin Infect Dis. 2021 Jul 1;73(1):e252-e255. doi: 10.1093/cid/ciaa1246.
8
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10
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Clin Case Rep. 2017 Dec 7;6(1):165-169. doi: 10.1002/ccr3.1309. eCollection 2018 Jan.