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一例沙门氏菌性心内膜炎病例报告及文献综述

A Case Report of Salmonella sp. Endocarditis and Literature Review.

作者信息

Do Rego Hermann, Moeuf Yoann, Azarine Arshid, Kloekner Martin, Pilmis Benoit

机构信息

Clinical Microbiology Mobile Team (EMMC), Hospital Paris Saint-Joseph, Paris, FRA.

Department of Cardiology, Hospital Paris Saint-Joseph, Paris, FRA.

出版信息

Cureus. 2025 Feb 17;17(2):e79142. doi: 10.7759/cureus.79142. eCollection 2025 Feb.

Abstract

sp. is a rare cause of infective endocarditis (IE). We present a case of endocarditis diagnosed in an 80-year-old man who had undergone multiple aortic valve replacements and had a recurrence of sp. bacteremia with hyperfixation on positron emission tomography (PET) scan and an aortic periprosthetic false aneurysm suggestive of a paravalvular abscess on cardiac scan. Treatment consisted of aortic valve replacement and curative antibiotic therapy with ceftriaxone, and the patient is still alive and asymptomatic on suppressive antibiotics with cotrimoxazole. We also present a review of sp. IE in the PubMed and Google Scholar databases between 2014 and 2023. A total of 39 patients were included, including one case managed by our team. The median age was 55 years, and the most commonly involved valves were mitral and aortic in 43% and 41% of cases, respectively. Thirty-one percent of patients had prosthetic valve endocarditis subsp. serovar Enteritidis was the main pathogen in 41% of patients. Surgery was performed in 36% of cases. The most common antibiotic was a third-generation cephalosporin in 67% of cases, and the median duration of treatment was six weeks. Mortality under treatment was 10%. In the case of recurrent bacteremia, endocarditis must be considered.

摘要

[细菌名称]是感染性心内膜炎(IE)的罕见病因。我们报告一例80岁男性的心内膜炎病例,该患者曾多次接受主动脉瓣置换术,出现[细菌名称]菌血症复发,正电子发射断层扫描(PET)显示高度摄取,心脏扫描提示主动脉人工瓣膜周围假性动脉瘤,提示瓣周脓肿。治疗包括主动脉瓣置换术及使用头孢曲松进行根治性抗生素治疗,患者在接受复方新诺明抑制性抗生素治疗后仍存活且无症状。我们还对2014年至2023年期间PubMed和谷歌学术数据库中[细菌名称]感染性心内膜炎的相关文献进行了综述。共纳入39例患者,包括我们团队管理的1例病例。中位年龄为55岁,最常受累的瓣膜分别为二尖瓣和主动脉瓣,各占病例的43%和41%。31%的患者患有人工瓣膜心内膜炎。[细菌名称]肠炎亚种是41%患者的主要病原体。36%的病例进行了手术。67%的病例最常用的抗生素是第三代头孢菌素,中位治疗持续时间为六周。治疗期间的死亡率为10%。对于复发性菌血症,必须考虑心内膜炎。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a220/11923509/34e6f56e2a70/cureus-0017-00000079142-i03.jpg

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