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双人工瓣膜患者难治性沙门氏菌人工瓣膜心内膜炎并发脾梗死和主动脉假性动脉瘤:一例报告

Refractory Salmonella Prosthetic Valve Endocarditis Complicated by Splenic Infarction and Aortic Pseudoaneurysm in a Patient with Double Prosthetic Valves: A Case Report.

作者信息

Alhamadh Moustafa S, Alanazi Rakan B, Alhowaish Thamer Saad, Alhabeeb Abdulrahman Yousef, Algarni Sultan T, Wadaan Osama Mohaamad, Suliman Ihab, Al-Ghamdi Mohammed Ghormalla

机构信息

College of Medicine, King Saud bin Abdulaziz University for Health Sciences (KSAU-HS), Ministry of the National Guard-Health Affairs, Riyadh 14611, Saudi Arabia.

King Abdullah International Medical Research Center, Ministry of the National Guard-Health Affairs, Riyadh 11481, Saudi Arabia.

出版信息

Diagnostics (Basel). 2022 Aug 16;12(8):1982. doi: 10.3390/diagnostics12081982.

DOI:10.3390/diagnostics12081982
PMID:36010333
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9407200/
Abstract

Endocarditis is an extremely rare complication of with an incidence of 0.2-0.4%. It is a destructive and invasive infection that follows a highly complicated course and carries a high mortality rate that exceeds 45%. Multiple predisposing factors for endocarditis have been described in the literature, including human immunodeficiency virus infection, congenital heart diseases, and the presence of a prosthetic valve. Herein, we report a case of prosthetic valve endocarditis complicated by splenic infarction and aortic pseudoaneurysm presenting as a month-long history of fluctuating fever, chills, and rigors, accompanied by occasional cough and shortness of breath in a 55-year-old female with aortic and mitral valves replacement and multiple comorbidities. She was diagnosed by multiple radiographic studies and successfully treated with the Commando procedure and a long course of IV antibiotics.

摘要

心内膜炎是一种极其罕见的并发症,发病率为0.2 - 0.4%。它是一种具有破坏性和侵袭性的感染,病程高度复杂,死亡率超过45%。文献中描述了心内膜炎的多种易感因素,包括人类免疫缺陷病毒感染、先天性心脏病以及人工瓣膜的存在。在此,我们报告一例人工瓣膜心内膜炎合并脾梗死和主动脉假性动脉瘤的病例,患者为一名55岁女性,有主动脉瓣和二尖瓣置换史且伴有多种合并症,表现为长达一个月的发热、寒战和 rigor(此处原文有误,可能是rigors,意为寒战)波动病史,伴有偶尔咳嗽和气短。她通过多项影像学检查确诊,并通过“突击手术”(Commando procedure)和长期静脉使用抗生素成功治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a41/9407200/082738842eb3/diagnostics-12-01982-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a41/9407200/bd87c9bf3d5b/diagnostics-12-01982-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a41/9407200/861b059b8278/diagnostics-12-01982-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a41/9407200/3d8a64e9be0f/diagnostics-12-01982-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a41/9407200/b4ecfc677494/diagnostics-12-01982-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a41/9407200/552d27038752/diagnostics-12-01982-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a41/9407200/082738842eb3/diagnostics-12-01982-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a41/9407200/bd87c9bf3d5b/diagnostics-12-01982-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a41/9407200/861b059b8278/diagnostics-12-01982-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a41/9407200/3d8a64e9be0f/diagnostics-12-01982-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a41/9407200/b4ecfc677494/diagnostics-12-01982-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a41/9407200/552d27038752/diagnostics-12-01982-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a41/9407200/082738842eb3/diagnostics-12-01982-g006.jpg

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本文引用的文献

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2
Salmonella Serogroup C: Current Status of Vaccines and Why They Are Needed.沙门氏菌C血清群:疫苗的现状及为何需要疫苗
Clin Vaccine Immunol. 2016 Sep 6;23(9):737-45. doi: 10.1128/CVI.00243-16. Print 2016 Sep.
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2015 ESC Guidelines for the management of infective endocarditis: The Task Force for the Management of Infective Endocarditis of the European Society of Cardiology (ESC). Endorsed by: European Association for Cardio-Thoracic Surgery (EACTS), the European Association of Nuclear Medicine (EANM).
食源性感染与:当前的主要预防工具及未来展望
Vaccines (Basel). 2024 Dec 31;13(1):29. doi: 10.3390/vaccines13010029.
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Emerging Strategies against Non-Typhoidal : From Pathogenesis to Treatment.针对非伤寒型的新兴策略:从发病机制到治疗
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Non-typhoidal prosthetic valve endocarditis.非伤寒性人工瓣膜心内膜炎。
BMJ Case Rep. 2023 Nov 27;16(11):e256540. doi: 10.1136/bcr-2023-256540.
2015年欧洲心脏病学会(ESC)感染性心内膜炎管理指南:欧洲心脏病学会(ESC)感染性心内膜炎管理工作组。认可机构:欧洲心胸外科学会(EACTS)、欧洲核医学协会(EANM)。
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