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加沙战争对乳腺癌患者生活质量影响的横断面调查。

Cross-sectional investigation of the effects of the war in Gaza on quality-of-life of breast cancer patients.

作者信息

Hejaz Hatem A

机构信息

Faculty of Pharmacy, Arab American University, Zababdeh, Jenin, State of Palestine.

出版信息

East Mediterr Health J. 2025 Mar 3;31(2):101-108. doi: 10.26719/2025.31.2.101.

Abstract

BACKGROUND

The current conflict in Gaza has had a major impact on the residents, especially those with chronic illnesses such as breast cancer.

AIM

To evaluate the impact of the war in Gaza on the quality-of-life of breast cancer patients.

METHODS

This cross-sectional study used the European Organization for Research and Treatment of Cancer Quality-of-life Questionnaire-Core 30 (EORTC QLQ-C30) and the Breast Cancer-Specific 23-Item (BR-23) questionnaires to obtain data from 300 breast cancer patients (residents and refugees) in Rafah, Gaza, between 1 February and 1 May 2024. The data were analysed using SPSS version 25 and statistical significance was established at P < 0.05.

RESULTS

The participants had a mean age of 52 years, 70% were married and 60% had children. Significant relationships were found between exposure to war-related events and lower quality-of-life across all measured domains (P < 0.01). Exposure to conflict was associated with significantly lower cognitive, role, emotional, and physical functioning scores. Fatigue (70%), pain (60%) and financial difficulties (55%) were the most common problems. Significant decreases in quality-of-life were observed in conjunction with conflict exposure. Individuals displayed deficits in their social, emotional and physical welfare. There was a strong link between low quality-of-life and issues such as violence, displacement and disruption of health care services. Physical functioning was a critical domain in the assessment of quality-of-life.

CONCLUSION

The war in Gaza has significantly reduced the quality-of-life of breast cancer patients, indicating that conflict negatively affects social, emotional and physical health. This study highlights the need for focused treatment and comprehensive support to address these complex issues.

摘要

背景

当前加沙的冲突对居民产生了重大影响,尤其是那些患有乳腺癌等慢性病的居民。

目的

评估加沙战争对乳腺癌患者生活质量的影响。

方法

这项横断面研究使用了欧洲癌症研究与治疗组织生活质量核心问卷30(EORTC QLQ-C30)和乳腺癌特异性23项问卷(BR-23),于2024年2月1日至5月1日期间从加沙拉法的300名乳腺癌患者(居民和难民)中获取数据。使用SPSS 25版对数据进行分析,P<0.05为具有统计学意义。

结果

参与者的平均年龄为52岁,70%已婚,60%育有子女。在所有测量领域中,接触与战争相关的事件与较低的生活质量之间存在显著关系(P<0.01)。接触冲突与认知、角色、情感和身体功能得分显著降低相关。疲劳(70%)、疼痛(60%)和经济困难(55%)是最常见的问题。随着冲突暴露,生活质量显著下降。个体在社会、情感和身体福利方面存在缺陷。低生活质量与暴力、流离失所和医疗服务中断等问题之间存在密切联系。身体功能是生活质量评估中的一个关键领域。

结论

加沙战争显著降低了乳腺癌患者的生活质量,表明冲突对社会、情感和身体健康产生负面影响。本研究强调需要针对性治疗和全面支持来解决这些复杂问题。

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