胆囊收缩素和蛙皮素抑制因食物奖励而产生的操作性反应。

Cholecystokinin and bombesin suppress operant responding for food reward.

作者信息

Babcock A M, Livosky M, Avery D D

出版信息

Pharmacol Biochem Behav. 1985 May;22(5):893-5. doi: 10.1016/0091-3057(85)90543-x.

Abstract

The effects of intraperitoneal injections of cholecystokinin (CCK) and bombesin (BBS) on food-rewarded operant responding were investigated. Response rates were significantly suppressed following administrations of CCK (0.7, 1.4, and 2.9 micrograms/kg). The effects appeared to be dose dependent. Responding was also suppressed following injections of BBS (6 and 16 micrograms/kg). These results confirm and extend previous findings concerning the possible function of these peptides.

摘要

研究了腹腔注射胆囊收缩素（CCK）和蛙皮素（BBS）对食物强化操作性反应的影响。注射CCK（0.7、1.4和2.9微克/千克）后，反应率显著受到抑制。这种影响似乎具有剂量依赖性。注射BBS（6和16微克/千克）后反应也受到抑制。这些结果证实并扩展了先前关于这些肽可能功能的研究发现。