猴痘Ib分支的再度出现：一场全球卫生紧急事件及关切问题。

The resurgence of monkeypox clade Ib: a global health emergency and concern.

作者信息

Kumar Suresh, Subramaniam Gunasekaran, Senthil Kumar K J

机构信息

Faculty of Health and Life Sciences, Management and Science University, Seksyen 13, Shah Alam, Selangor, 40100, Malaysia.

Kavli Institute for Nanoscience Discovery, Dorothy Crowfoot Hodgkin Building University of Oxford, South Parks Rd, Oxford, UK.

出版信息

Arch Virol. 2025 Mar 21;170(4):84. doi: 10.1007/s00705-025-06270-0.

DOI:10.1007/s00705-025-06270-0

PMID:40116967

Abstract

The resurgence of monkey pox (mpox) virus clade Ib, which was declared a global health emergency in August 2024, poses a significant threat worldwide. Initially contained through public health measures, the increased transmissibility of clade Ib strains compared with that of previous strains has led to a rapid rise in cases, particularly in Central Africa. The resurgence highlights disparities in diagnostic capabilities and healthcare infrastructure, leading to underreporting in resource-limited regions. New variants could evade immunity, necessitating continued vaccination efforts for high-risk groups. This review discusses the epidemiological situation, recent outbreaks, clinical features, and public health response, emphasizing the urgent need for global coordination in diagnostic, prevention, and treatment strategies.

摘要

猴痘（mpox）病毒B1分支的再度流行在全球构成了重大威胁，该分支于2024年8月被宣布为全球卫生紧急情况。最初通过公共卫生措施得到控制，但与先前毒株相比，B1分支毒株的传播性增强，导致病例迅速增加，尤其是在中非地区。此次再度流行凸显了诊断能力和医疗保健基础设施方面的差异，导致资源有限地区的病例报告不足。新变种可能逃避免疫，因此有必要继续为高危人群开展疫苗接种工作。本综述讨论了流行病学情况、近期疫情、临床特征和公共卫生应对措施，强调迫切需要在诊断、预防和治疗策略方面进行全球协调。