Koç Huriye Aybüke, Güney Cansu Altınöz, Önal Bedia Sultan
Department of Dermatology, Prof. Dr. A. Ilhan Ozdemir State Hospital, Giresun, Turkey.
Department of Dermatology, Dinar State Hospital, Afyonkarahisar, Türkiye.
Dermatol Pract Concept. 2025 Jan 30;15(1):4854. doi: 10.5826/dpc.1501a4854.
Accompanying comorbidities in acne vulgaris (AV) patients affect treatment adherence.
The purpose of this study was to investigate the relationship between treatment compliance and attention deficit hyperactivity disorder (ADHD) in adolescents with AV.
This study included 140 patients with AV. At the beginning of the treatment, each patient acne severity was assessed, and the Conners-Wells Adolescent Self-Report Scale-Long Form (CASS-L) was administered. The Morisky Medication Adherence Scale (MMAS-8) was used to assess treatment adherence. The treatment response was assessed using a six-point scale.
Significant differences were found in the scores on the 10 subscales of the CASS-L among the 3 groups. The Global Acne Grading System (GAGS) scores showed a positive correlation with the scores of the subscales of the CASS-L, with 3 of them at a moderate level and 7 at a weak level. Five MMAS subscales had a weak correlation and 5 had a moderate correlation with the CASS-L subscale scores. The 9 subscales and the treatment response showed a slight negative correlation.
ADHD is one of the many psychiatric comorbidities that frequently coexist with acne vulgaris. Its treatment is long-term and achieving a good treatment response relies heavily on patient adherence. Our study, which showed a decrease in acne treatment adherence and response as ADHD symptoms increased, will raise awareness among dermatologists to be more vigilant in their approach to this patient group.
寻常痤疮(AV)患者的伴发合并症会影响治疗依从性。
本研究旨在调查患有AV的青少年的治疗依从性与注意力缺陷多动障碍(ADHD)之间的关系。
本研究纳入了140例AV患者。在治疗开始时,评估每位患者的痤疮严重程度,并使用康纳斯-韦尔斯青少年自评量表长式(CASS-L)进行测评。使用莫斯基 Medication 依从性量表(MMAS-8)评估治疗依从性。使用六点量表评估治疗反应。
在3组患者中,CASS-L的10个分量表得分存在显著差异。全球痤疮分级系统(GAGS)得分与CASS-L分量表得分呈正相关,其中3个为中度相关,7个为弱相关。MMAS的5个分量表与CASS-L分量表得分呈弱相关,5个呈中度相关。9个分量表与治疗反应呈轻微负相关。
ADHD是与寻常痤疮经常共存的众多精神合并症之一。其治疗是长期的,要取得良好的治疗反应很大程度上依赖于患者的依从性。我们的研究表明,随着ADHD症状的增加,痤疮治疗的依从性和反应会降低,这将提高皮肤科医生对该患者群体治疗时的警惕性。