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青少年寻常痤疮与注意力缺陷多动障碍之间的关系:一项横断面研究。

Relationship between acne vulgaris and attention deficit hyperactivity disorder in adolescent: A cross-sectional study.

作者信息

Koç Huriye Aybüke, Önal Bedia Sultan

机构信息

Department of Dermatology, Prof. Dr. A. İlhan Özdemir State Hospital, Giresun, Turkey.

Department of Child and Adolescent Mental Health and Diseases, Faculty of Medicine, Giresun University, Giresun, Turkey.

出版信息

J Dermatol. 2025 Jan;52(1):50-55. doi: 10.1111/1346-8138.17435. Epub 2024 Aug 30.

Abstract

High androgen hormone exposure in intrauterine life is held to be responsible for the etiopathogenesis of both acne vulgaris (AV) and attention-deficit hyperactivity disorder (ADHD). In this study, we aimed to investigate the prevalence of ADHD in AV patients. Patients between the ages of 12 and 17, diagnosed with AV and a control group were included in the study. The Conners-Wells Adolescent Self-Report Scale-Long Form (CASS-L) was applied to both groups to determine the severity of the ADHD. Ninety-eight patients diagnosed with AV and 96 healthy controls participated in the study. All parameters of the CASS-L were found to be significantly higher in AV patients compared to the control group. In addition, with the severity of the Global Acne Grading System, a positive low level among conduct problems (r = 0.223), cognitive problems (r = 0.271), ADHD index (r = 0.238), inattention (r = 0.238), and a positive moderate level among hyperactivity (r = 0.349), hyperactivity-impulsivity (r = 0.414), and total score (r = 0.429). According to our results, patients diagnosed with AV were more prone to ADHD than the control group. Our study showed that adolescent patients diagnosed with AV were more prone to ADHD than people of similar age and gender without a diagnosis of AV. It should be noted that AV is not only a dermatological disease but may also be accompanied by psychiatric morbidities.

摘要

子宫内生活期间高雄激素激素暴露被认为是寻常痤疮(AV)和注意力缺陷多动障碍(ADHD)发病机制的原因。在本研究中,我们旨在调查AV患者中ADHD的患病率。年龄在12至17岁之间、被诊断为AV的患者和一个对照组被纳入研究。对两组均应用康纳斯-韦尔斯青少年自评量表长式(CASS-L)来确定ADHD的严重程度。98例被诊断为AV的患者和96例健康对照参与了研究。发现AV患者的CASS-L所有参数均显著高于对照组。此外,随着全球痤疮分级系统严重程度的增加,品行问题(r = 0.223)、认知问题(r = 0.271)、ADHD指数(r = 0.238)、注意力不集中(r = 0.238)呈低水平正相关,多动(r = 0.349)、多动冲动(r = 0.414)和总分(r = 0.429)呈中等水平正相关。根据我们的结果,被诊断为AV的患者比对照组更容易患ADHD。我们的研究表明,被诊断为AV的青少年患者比未被诊断为AV的年龄和性别相似的人更容易患ADHD。应该注意的是,AV不仅是一种皮肤病,还可能伴有精神疾病。

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