Stromstad S A, Kauffman H M, Sampson D, Stawicki A T
Department of Surgery, Medical College of Wisconsin, Milwaukee.
Surg Forum. 1978;29:376-7.
This randomized, double-blind study failed to show any therapeutic benefit of a 30-mg/kg bolus over a 3-mg/kg bolus of methylprednisolone for the treatment of acute kidney transplant rejection. Since there was a slight associated increase in infections and septic mortality, routine use of high-dose methylprednisolone bolus therapy is not recommended or justified.
这项随机双盲研究未能表明，对于治疗急性肾移植排斥反应，30毫克/千克甲泼尼龙推注剂量比3毫克/千克推注剂量有任何治疗益处。由于感染及脓毒症死亡率略有相关增加，不推荐或不支持常规使用大剂量甲泼尼龙推注疗法。
