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化疗联合调制式电致热疗法(mEHT)可将初诊时无法手术的食管癌转变为可手术疾病。

Chemoradiotherapy Combined With Modulated Electro-Hyperthermia (mEHT) Converts Initially Inoperable Esophageal Cancer to Operable Disease.

作者信息

Kuo Deng-Yu, Shueng Pei-Wei, Wang Shan-Ying, How Cheng-Hung, Hsu Chen-Xiong

机构信息

Division of Radiation Oncology, Department of Radiology, Far Eastern Memorial Hospital, New Taipei, Taiwan.

Faculty of Medicine, School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.

出版信息

Thorac Cancer. 2025 Mar;16(6):e70044. doi: 10.1111/1759-7714.70044.

Abstract

This case report demonstrated the effectiveness of combining chemoradiotherapy (CCRT) with modulated electro-hyperthermia (mEHT) in converting initially inoperable esophageal cancer into an operable condition. A 60-year-old male with stage IVB lower third esophageal squamous cell carcinoma (cT3N2M1) experienced significant tumor shrinkage (ypT2N0M0) and a notable metabolic response, which enabled successful surgical removal. This treatment approach highlights the potential of mEHT as a valuable addition to the comprehensive management of esophageal cancer.

摘要

本病例报告证明了化疗放疗(CCRT)与调制式电高热疗法(mEHT)相结合在将最初无法手术的食管癌转变为可手术状态方面的有效性。一名60岁患有IVB期食管下三分之一鳞状细胞癌(cT3N2M1)的男性经历了显著的肿瘤缩小(ypT2N0M0)和明显的代谢反应,从而得以成功进行手术切除。这种治疗方法凸显了mEHT作为食管癌综合管理中有价值补充手段的潜力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f32/11928742/ef15470b1da5/TCA-16-e70044-g001.jpg

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