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[尤因肉瘤与胫骨纤维发育不良的关联。附病例报告]

[Association of Ewing's sarcoma with fibrous dysplasia of the tibia. Apropos of a case report].

作者信息

Roth A, Touzet P, Rigault P

出版信息

Rev Chir Orthop Reparatrice Appar Mot. 1985;71(2):133-7.

PMID:4011972
Abstract

The authors have observed a child of 14 presenting fibrous dysplasia localised to the right femur and right tibia and complicated by an Ewing's sarcoma of the right tibia. The complication was marked only by pain and the radiographs were not typical. It was diagnosed only by microscopic examination after biopsy. Scintigraphy did not reveal any other site of fibrous dysplasia. The tibia was treated by a reinforcing nail followed by radiotherapy and chemotherapy. After a 4 year follow-up there was neither recurrence nor metastasis. After a review of the literature it is concluded that this combination was purely accidental and that there is no known relationship between Ewing's sarcoma and Jaffe-Lichtenstein type of fibrous dysplasia. It is remarkable that the sarcoma was not typical clinically and that the satisfactory result was probably related to very early treatment.

摘要

作者观察到一名14岁儿童,其纤维结构不良局限于右股骨和右胫骨,并并发右胫骨尤因肉瘤。该并发症仅表现为疼痛,X线片并不典型。仅在活检后通过显微镜检查才得以确诊。骨闪烁显像未显示纤维结构不良的其他部位。胫骨采用加强钉治疗,随后进行放疗和化疗。经过4年随访,既无复发也无转移。在查阅文献后得出结论,这种组合纯属偶然,尤因肉瘤与贾菲 - 利希滕斯坦型纤维结构不良之间尚无已知关联。值得注意的是,肉瘤在临床上并不典型,而满意的结果可能与非常早期的治疗有关。

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