• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Polygenic Inheritance for Common Comorbidities Associated With Congenital Heart Disease.

作者信息

Thompson Jamie-Lee M, Tarr Ingrid S, Rath Emma M, Troup Michael, Ip Eddie K K, Blue Gillian M, Winlaw David S, Dunwoodie Sally L, Giannoulatou Eleni

机构信息

Victor Chang Cardiac Research Institute, Darlinghurst, Sydney, Australia.

Victor Chang Cardiac Research Institute, Darlinghurst, Sydney, Australia; School of Clinical Medicine, St Vincent's Healthcare Clinical Campus, Faculty of Medicine and Health, UNSW Sydney, Kensington, Australia.

出版信息

JACC Adv. 2025 Apr;4(4):101673. doi: 10.1016/j.jacadv.2025.101673. Epub 2025 Mar 21.

DOI:10.1016/j.jacadv.2025.101673
PMID:40120216
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11976230/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f7e5/11976230/4189704d9946/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f7e5/11976230/4189704d9946/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f7e5/11976230/4189704d9946/gr1.jpg

相似文献

1
Polygenic Inheritance for Common Comorbidities Associated With Congenital Heart Disease.先天性心脏病相关常见合并症的多基因遗传
JACC Adv. 2025 Apr;4(4):101673. doi: 10.1016/j.jacadv.2025.101673. Epub 2025 Mar 21.
2
Polygenic Risk Score-Based Association Analysis Identifies Genetic Comorbidities Associated with Age-Related Hearing Difficulty in Two Independent Samples.基于多基因风险评分的关联分析确定了与两个独立样本中年龄相关性听力困难相关的遗传共病。
J Assoc Res Otolaryngol. 2024 Aug;25(4):387-406. doi: 10.1007/s10162-024-00947-0. Epub 2024 May 23.
3
Predictive Accuracy of a Polygenic Risk Score Compared With a Clinical Risk Score for Incident Coronary Heart Disease.多基因风险评分与临床风险评分预测冠心病事件的准确性比较。
JAMA. 2020 Feb 18;323(7):627-635. doi: 10.1001/jama.2019.21782.
4
Association of Genetic Variation With Cirrhosis: A Multi-Trait Genome-Wide Association and Gene-Environment Interaction Study.遗传变异与肝硬化的关联：一项多性状全基因组关联和基因-环境相互作用研究。
Gastroenterology. 2021 Apr;160(5):1620-1633.e13. doi: 10.1053/j.gastro.2020.12.011. Epub 2020 Dec 11.
5
An 8-SNP LDL Cholesterol Polygenic Score: Associations with Cardiovascular Risk Traits, Familial Hypercholesterolemia Phenotype, and Premature Coronary Heart Disease in Central Romania.一个包含 8 个单核苷酸多态性的 LDL 胆固醇多基因评分：与心血管风险特征、家族性高胆固醇血症表型和罗马尼亚中部的早发性冠心病的相关性。
Int J Mol Sci. 2024 Sep 18;25(18):10038. doi: 10.3390/ijms251810038.
6
Polygenic score analysis identifies distinct genetic risk profiles in Alzheimer's disease comorbidities.多基因评分分析确定了阿尔茨海默病合并症中不同的遗传风险概况。
Sci Rep. 2025 Apr 3;15(1):11407. doi: 10.1038/s41598-025-95755-8.
7
Genetic risk for major depressive disorder and loneliness in sex-specific associations with coronary artery disease.性别特异性关联中，主要抑郁障碍和孤独的遗传风险与冠状动脉疾病的关系。
Mol Psychiatry. 2021 Aug;26(8):4254-4264. doi: 10.1038/s41380-019-0614-y. Epub 2019 Dec 3.
8
Polygenic Risk Scores and Extreme Coronary Artery Calcium Phenotypes (CAC=0 and CAC≥1000) in Adults ≥75 Years Old: The ARIC Study.多基因风险评分与≥75 岁成年人的极重度冠状动脉钙表型（CAC=0 和 CAC≥1000）：ARIC 研究。
Circ Cardiovasc Imaging. 2024 Nov;17(11):e016377. doi: 10.1161/CIRCIMAGING.123.016377. Epub 2024 Nov 13.
9
Association between genetic liability to physical health conditions and comorbidities in individuals with severe mental illness: an analysis of two cross-sectional observational studies in the UK.严重精神疾病患者身体健康状况的遗传易感性与共病之间的关联：对英国两项横断面观察性研究的分析
Lancet Psychiatry. 2025 Jun;12(6):447-456. doi: 10.1016/S2215-0366(25)00123-3. Epub 2025 May 5.
10
Polygenic Contribution to Low-Density Lipoprotein Cholesterol Levels and Cardiovascular Risk in Monogenic Familial Hypercholesterolemia.多基因对单基因家族性高胆固醇血症患者低密度脂蛋白胆固醇水平和心血管风险的贡献。
Circ Genom Precis Med. 2020 Oct;13(5):515-523. doi: 10.1161/CIRCGEN.120.002919. Epub 2020 Aug 13.

本文引用的文献

1
A multitiered analysis platform for genome sequencing: Design and initial findings of the Australian Genomics Cardiovascular Disorders Flagship.用于基因组测序的多层分析平台：澳大利亚基因组学心血管疾病旗舰项目的设计与初步发现
Genet Med Open. 2024 Mar 25;2:101842. doi: 10.1016/j.gimo.2024.101842. eCollection 2024.
2
Acquired Comorbidities in Adults with Congenital Heart Disease: An Analysis of the German National Register for Congenital Heart Defects.成人先天性心脏病的获得性合并症：德国先天性心脏病国家登记册分析
J Clin Med. 2021 Jan 16;10(2):314. doi: 10.3390/jcm10020314.
3
The Medical Genome Reference Bank contains whole genome and phenotype data of 2570 healthy elderly.
医学基因组参考资料库包含了 2570 位健康老年人的全基因组和表型数据。
Nat Commun. 2020 Jan 23;11(1):435. doi: 10.1038/s41467-019-14079-0.
4
A global reference for human genetic variation.人类遗传变异的全球参考。
Nature. 2015 Oct 1;526(7571):68-74. doi: 10.1038/nature15393.