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英格兰日常生活无残疾预期寿命的地区层面社会经济不平等:一项建模研究。

Area-level socioeconomic inequalities in activities of daily living disability-free life expectancy in England: a modelling study.

作者信息

Davies Laurie E, Sinclair David R, Todd Christopher, Hanratty Barbara, Matthews Fiona E, Kingston Andrew

机构信息

National Institute for Health and Care Research Policy Research Unit in Healthy Ageing, Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK.

National Institute for Health and Care Research Policy Research Unit in Healthy Ageing, School of Health Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.

出版信息

Lancet Healthy Longev. 2025 Apr;6(4):100700. doi: 10.1016/j.lanhl.2025.100700. Epub 2025 Mar 19.

Abstract

BACKGROUND

More evidence of socioeconomic inequalities in disability-free life expectancy (DFLE) is needed to help develop approaches to narrow the gap between the most and least socioeconomically deprived people. Activities of daily living (ADL) disability represents the most severe and expensive disablement stage. Using combined longitudinal data, we aimed to quantify area-level socioeconomic inequalities in ADL-DFLE and the total person-years lived with ADL disability, in older men and women in England.

METHODS

In this modelling study, we harmonised data on ADL disability, area deprivation, age, and self-reported gender for individuals aged 50 years or older from three longitudinal studies in England: the English Longitudinal Study of Ageing (n=11 337), the Cognitive Function and Ageing Study II (n=7469), and the Newcastle 85+ Study (n=847). We used multistate modelling, and calculated the remaining life expectancy with and without ADL disability by gender and area-level socioeconomic status (<20%, 20-80%, and >80% of Index of Multiple Deprivation). From these data and Office for National Statistics population figures for the year 2024, we estimated the extra person-years lived with ADL disability by those aged 65 years from the most socioeconomically deprived areas.

FINDINGS

Those living in the least deprived areas had a reduced risk of ADL disability compared with those in the most deprived areas (hazard ratio [HR] 0·61 [95% CI 0·55-0·69]; p<0·0001), as did those in the middle area-level socioeconomic group (HR 0·76 [0·69-0·84]; p<0·0001). Increasing area-level socioeconomic disadvantage was associated with reduced life expectancy and more time spent with ADL disability, particularly for women. Living in the most disadvantaged areas was associated with people having ADL disability 11·0 years earlier for men and 12·0 years earlier for women, compared with living in the least deprived areas. An extra 59 000 person-years for men and 88 000 person-years for women were lived with ADL disability by those in the most deprived areas, at the population level, compared with the least deprived areas.

INTERPRETATION

Targeted policies to address underlying socioeconomic inequalities in health are likely to be the long-term definitive solution.

FUNDING

National Institute for Health and Care Research Policy Research Unit in Healthy Ageing.

摘要

背景

需要更多关于无残疾预期寿命(DFLE)社会经济不平等的证据,以帮助制定缩小社会经济最贫困和最不贫困人群之间差距的方法。日常生活活动(ADL)残疾代表了最严重且成本最高的残疾阶段。我们利用合并的纵向数据,旨在量化英格兰老年男性和女性中ADL-DFLE的地区层面社会经济不平等以及ADL残疾状态下的总人年数。

方法

在这项建模研究中,我们整合了来自英格兰三项纵向研究中50岁及以上个体的ADL残疾、地区贫困程度、年龄和自我报告性别的数据:英格兰老年纵向研究(n = 11337)、认知功能与衰老研究II(n = 7469)以及纽卡斯尔85岁及以上研究(n = 847)。我们采用多状态建模,并按性别和地区层面社会经济状况(多重剥夺指数的<20%、20 - 80%和>80%)计算有无ADL残疾情况下的剩余预期寿命。根据这些数据以及英国国家统计局2024年的人口数据,我们估算了来自社会经济最贫困地区的65岁人群在ADL残疾状态下多活的人年数。

结果

与最贫困地区的人相比,生活在最不贫困地区的人ADL残疾风险降低(风险比[HR] 0.61 [95%置信区间0.55 - 0.69];p < 0.0001),中等地区层面社会经济群体的人也是如此(HR 0.76 [0.69 - 0.84];p < 0.0001)。地区层面社会经济劣势增加与预期寿命降低以及ADL残疾状态下花费的时间增多相关,尤其是对女性而言。与生活在最不贫困地区相比,生活在最贫困地区的男性出现ADL残疾的时间要早11.0年,女性要早12.0年。在人口层面,与最不贫困地区相比,最贫困地区的男性因ADL残疾多活59000人年,女性多活88000人年。

解读

针对健康方面潜在社会经济不平等的针对性政策可能是长期的最终解决方案。

资金来源

国家健康与照护研究所在健康老龄化方面的政策研究部门。

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