Cazzato G, Torre P, Antonello R, Bisin Z
Riv Neurol. 1985 Mar-Apr;55(2):109-15.
In a 59 years old patient suffering from a non stenotic atheroma of the internal right carotid artery, 12 attacks of "amaurosis fugax" (a.m.) affecting the right eye occurred over a period of 36 days. Ticlopidine at doses of 500 mg and subsequently of 250 mg per day was administered and the attacks of "amaurosis fugax" briskly stopped. In the 8 month period following the occurrence of the last episode of monocular blindness, the patient continued the therapy with ticlopidine and no visual disturbances were more reported. The most likely pathogenetic hypotheses of "amaurosis fugax" in the present case are discussed as well as the possibility that the relation between the attacks of a.m. and the beginning of the treatment with ticlopidine might be fortuitous.
一名59岁患者，右侧颈内动脉有非狭窄性动脉粥样硬化，在36天内右眼发生了12次“一过性黑矇”发作。给予每日500毫克随后为250毫克的噻氯匹定治疗，“一过性黑矇”发作迅速停止。在最后一次单眼失明发作后的8个月期间，患者继续使用噻氯匹定治疗，未再报告有视觉障碍。本文讨论了本例中“一过性黑矇”最可能的发病机制假说，以及一过性黑矇发作与噻氯匹定治疗开始之间的关系可能是偶然的这种可能性。
