Resjö Svante, Kieu Nam P, Zahid Muhammad Awais, Lenman Marit, Andersson Björn, Andreasson Erik
Department of Plant Protection Biology, Swedish University of Agricultural Sciences, Lomma, Sweden.
Department of Forest Mycology and Plant Pathology, Swedish University of Agricultural Sciences, Uppsala, Sweden.
GM Crops Food. 2025 Dec;16(1):263-271. doi: 10.1080/21645698.2025.2479913. Epub 2025 Mar 23.
Potato ( L.) is an important global crop, but its production is severely impacted by late blight, caused by the pathogen . The economic burden of this disease is significant, and current control strategies rely mainly on fungicides, which face increasing regulatory and environmental constraints. To address this challenge, potatoes with resistance genes from wild potato relatives offer a promising solution. This study evaluated field resistance to late blight in potato lines (Maris Piper) containing the resistance genes and across three years (2018-2020) in Sweden. Field trials were conducted under natural infection conditions to assess disease resistance. Results showed that the transgenic lines conferred strong resistance to late blight compared to the susceptible control. However, slight late blight symptoms were observed in the transgenic lines. These results highlight the effectiveness of resistance genes in providing strong resistance, and emphasize the potential of stacking multiple R genes, including these genes to maintain efficacy. This research supports the development of resistant potato varieties as a sustainable alternative to chemical control, promoting food security and environmentally friendly agriculture.
马铃薯（茄属）是一种重要的全球性作物，但其生产受到由致病疫霉引起的晚疫病的严重影响。这种病害造成的经济负担巨大，当前的防治策略主要依赖杀菌剂，而杀菌剂面临着越来越多的监管和环境限制。为应对这一挑战，含有来自野生马铃薯近缘种抗性基因的马铃薯提供了一个有前景的解决方案。本研究在瑞典对含有抗性基因和的马铃薯品系（玛丽斯派珀）进行了为期三年（2018 - 2020年）的晚疫病田间抗性评估。在自然感染条件下进行田间试验以评估抗病性。结果表明，与感病对照相比，转基因品系对晚疫病具有较强抗性。然而，在转基因品系中观察到了轻微的晚疫病症状。这些结果突出了抗性基因在提供强抗性方面的有效性，并强调了堆叠多个R基因（包括这些基因）以维持药效的潜力。本研究支持开发抗性马铃薯品种作为化学防治的可持续替代方案，促进粮食安全和环境友好型农业。
