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一种用于实时检测感染性肺部疾病的新型超轻量级卷积神经网络模型。

A novel and ultralight convolutional neural network model for real-time detection of infectious lung diseases.

作者信息

Alqaissi Eman

机构信息

Informatics and Computer Systems, King Khalid University, Abha, Saudi Arabia.

Unit of Technical and Engineering Majors, King Khalid University, Abha, Saudi Arabia.

出版信息

Digit Health. 2025 Mar 21;11:20552076251318155. doi: 10.1177/20552076251318155. eCollection 2025 Jan-Dec.

DOI:10.1177/20552076251318155
PMID:40123883
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11930494/
Abstract

OBJECTIVE

Vectors that cause infectious lung diseases encompass viral, bacterial, fungal, and parasitic agents. Early detection of these infections is critical for timely diagnosis and effective treatment. Several studies have created solutions for early detection with varying performance, but with limitations such as image type specificity, lack of generalizability, potential overfitting, and bias problems. Our model effectively addresses these problems by using diverse image types, enhancing robustness, and generalizability across various contexts that aim for effective performance.

METHODS

This study creates an early detection model that works with both CT scans and X-ray images. We applied a convolutional neural network (CNN) model trained on diverse and large augmented datasets with fewer parameters. We then used a generative adversarial network (GAN) to validate our CNN model and create generalized synthetic images. The proposed model was trained primarily on COVID-19, pneumonia, and tuberculosis (TB) cases (n = 432,533 total augmented cases).

RESULTS

The proposed model is a lightweight and explainable model that assists with real-time detection, resulting in a better performance with an average accuracy of 97.93% with a standard deviation of 0.97%, average area under the curve (AUC) of 98.07%, average sensitivity of 98.46%, average specificity of 97.03%, average precision of 97.45%, and average F1 score of 97.95%.

CONCLUSION

The proposed CNN model offers a validation and generalization capability for diverse image types in real-time. We conducted a comparative analysis of our model with the most advanced research. The integration of our approach with other clinical systems and internet of things (IoT) devices is feasible.

摘要

目的

导致感染性肺部疾病的病原体包括病毒、细菌、真菌和寄生虫。早期检测这些感染对于及时诊断和有效治疗至关重要。多项研究提出了不同性能的早期检测解决方案,但存在图像类型特异性、缺乏通用性、潜在过拟合和偏差问题等局限性。我们的模型通过使用多种图像类型、增强鲁棒性以及在各种旨在实现有效性能的情境中的通用性,有效解决了这些问题。

方法

本研究创建了一个适用于CT扫描和X射线图像的早期检测模型。我们应用了一个在多样且大量的增强数据集上训练的参数较少的卷积神经网络(CNN)模型。然后,我们使用生成对抗网络(GAN)来验证我们的CNN模型并创建通用的合成图像。所提出的模型主要在新冠肺炎、肺炎和肺结核(TB)病例(总共432,533个增强病例)上进行训练。

结果

所提出的模型是一个轻量级且可解释的模型,有助于实时检测,性能更佳,平均准确率为97.93%,标准差为0.97%,平均曲线下面积(AUC)为98.07%,平均灵敏度为98.46%,平均特异性为97.03%,平均精确率为97.45%,平均F1分数为97.95%。

结论

所提出的CNN模型为多种图像类型提供了实时验证和通用能力。我们对我们的模型与最先进的研究进行了对比分析。我们的方法与其他临床系统和物联网(IoT)设备的集成是可行的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87af/11930494/2aee3f97b428/10.1177_20552076251318155-fig9.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87af/11930494/c9eb556efd0e/10.1177_20552076251318155-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87af/11930494/15c5a4aea165/10.1177_20552076251318155-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87af/11930494/4bcadcd46f1e/10.1177_20552076251318155-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87af/11930494/07d8744bf280/10.1177_20552076251318155-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87af/11930494/5ec42b4b7a85/10.1177_20552076251318155-fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87af/11930494/29127c5e5657/10.1177_20552076251318155-fig6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87af/11930494/529a353a3efd/10.1177_20552076251318155-fig7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87af/11930494/d4f4a9f57679/10.1177_20552076251318155-fig8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87af/11930494/2aee3f97b428/10.1177_20552076251318155-fig9.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87af/11930494/c9eb556efd0e/10.1177_20552076251318155-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87af/11930494/15c5a4aea165/10.1177_20552076251318155-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87af/11930494/4bcadcd46f1e/10.1177_20552076251318155-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87af/11930494/07d8744bf280/10.1177_20552076251318155-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87af/11930494/5ec42b4b7a85/10.1177_20552076251318155-fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87af/11930494/29127c5e5657/10.1177_20552076251318155-fig6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87af/11930494/529a353a3efd/10.1177_20552076251318155-fig7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87af/11930494/d4f4a9f57679/10.1177_20552076251318155-fig8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87af/11930494/2aee3f97b428/10.1177_20552076251318155-fig9.jpg

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