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降尿酸治疗实现脊柱痛风康复：一例报告

Spinal gout recovery with urate-lowering therapy: A case report.

作者信息

Huo Kunfang, Zhang Jialin, Lin Yanhua, Chen Qianyun, Zhong Han, Yang Bin

机构信息

Department of Nephrology, Immunology and Hematology The Fifth People's Hospital of Shunde District Foshan China.

Department of Rheumatology and Immunology Shunde Hospital, Southern Medical University (The First People's Hospital of Shunde) Foshan China.

出版信息

Clin Case Rep. 2025 Mar 20;13(3):e9426. doi: 10.1002/ccr3.9426. eCollection 2025 Mar.

DOI:10.1002/ccr3.9426
PMID:40124201
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11925811/
Abstract

The occurrence of spinal gout resulting in erosion of the superior articular process in patients with low back pain is uncommon, potentially leading to misdiagnosis and inappropriate treatment. Urate-lowering therapy may be beneficial in improving joint destruction and bone erosion, as evidenced by our case.

摘要

脊柱痛风导致下背痛患者的上关节突侵蚀的情况并不常见，可能会导致误诊和不恰当的治疗。如我们的病例所示，降尿酸治疗可能有助于改善关节破坏和骨质侵蚀。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f434/11925811/12188a00fc5e/CCR3-13-e9426-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f434/11925811/b8e5161f347d/CCR3-13-e9426-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f434/11925811/12188a00fc5e/CCR3-13-e9426-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f434/11925811/b8e5161f347d/CCR3-13-e9426-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f434/11925811/12188a00fc5e/CCR3-13-e9426-g001.jpg

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本文引用的文献

1
Beyond Medical Treatment: Surgical Treatment of Gout.超越医疗：痛风的手术治疗。
Curr Rheumatol Rep. 2020 Nov 24;23(1):1. doi: 10.1007/s11926-020-00969-6.
2
Gout in the Chest Misdiagnosed as Ankylosing Spondylitis.误诊为强直性脊柱炎的胸部痛风
Front Med (Lausanne). 2020 Oct 14;7:582444. doi: 10.3389/fmed.2020.582444. eCollection 2020.
3
Global epidemiology of gout: prevalence, incidence, treatment patterns and risk factors.全球痛风流行病学：患病率、发病率、治疗模式和危险因素。
Nat Rev Rheumatol. 2020 Jul;16(7):380-390. doi: 10.1038/s41584-020-0441-1. Epub 2020 Jun 15.
4
Effects of Febuxostat in Early Gout: A Randomized, Double-Blind, Placebo-Controlled Study.非布司他治疗早期痛风的疗效：一项随机、双盲、安慰剂对照研究。
Arthritis Rheumatol. 2017 Dec;69(12):2386-2395. doi: 10.1002/art.40233.
5
What makes gouty inflammation so variable?是什么导致痛风性炎症如此多变？
BMC Med. 2017 Aug 18;15(1):158. doi: 10.1186/s12916-017-0922-5.
6
The Global Burden of Latent Tuberculosis Infection: A Re-estimation Using Mathematical Modelling.潜伏性结核感染的全球负担：使用数学模型的重新估计
PLoS Med. 2016 Oct 25;13(10):e1002152. doi: 10.1371/journal.pmed.1002152. eCollection 2016 Oct.
7
Structural joint damage in gout.痛风中的关节结构损伤
Rheum Dis Clin North Am. 2014 May;40(2):291-309. doi: 10.1016/j.rdc.2014.01.006. Epub 2014 Feb 20.
8
Mechanisms of joint damage in gout: evidence from cellular and imaging studies.痛风性关节炎关节损伤的机制：细胞与影像学研究证据。
Nat Rev Rheumatol. 2012 Jan 10;8(3):173-81. doi: 10.1038/nrrheum.2011.207.
9
The pathogenesis of bone erosions in gouty arthritis.痛风性关节炎中骨侵蚀的发病机制。
Ann Rheum Dis. 2010 Nov;69(11):1907-12. doi: 10.1136/ard.2010.128454. Epub 2010 Aug 12.
10
Mechanisms of bone erosion in gout: a quantitative analysis using plain radiography and computed tomography.痛风性骨侵蚀的机制：一项使用X线平片和计算机断层扫描的定量分析
Ann Rheum Dis. 2009 Aug;68(8):1290-5. doi: 10.1136/ard.2008.094201. Epub 2008 Aug 15.