Department of Microbiology, ICMR-Regional Medical Research Centre (Department of Health Research, Ministry of Health and Family Welfare, Government of India), Bhubaneswar, Odisha, India.
Division of Epidemiology and Communicable Diseases, Indian Council of Medical Research, New Delhi, India.
Front Public Health. 2023 Jan 13;10:1074154. doi: 10.3389/fpubh.2022.1074154. eCollection 2022.
Antimicrobial resistance (AMR) has emerged as one of the major public health issues globally. This cross-sectional study determined knowledge, attitudes and practices (KAP) regarding antimicrobial use and AMR among rural communities of Tigiria (Odisha), India.
A semi-structured questionnaire based on socio-demographic characteristics, antibiotics usage, awareness of antimicrobial resistance, healthcare utilization and quality of life were asked to the participants using an electronic device with Open Data Kit. Descriptive statistics, independent -test and ANOVA were performed to analyze the variables.
A total of 1,003 participants were surveyed in the study from 25 villages of Tigiria. About 44.47% (95% CI: 41.36-47.60) of study participants have heard about antimicrobial medicines and 14.75% (95% CI: 12.65-17.13) of participants were involved in buying antibiotics without prescription over the counter. Around 20.14% (95% CI: 17.72-22.78) of participants, stopped taking antibiotics before completing the full course. The physical domain was the most affected with low scores compared to other domains of quality of life (QOL). The QOL scores were found significant ( < 0.05) across age, gender, education and ethnicity.
The study documented a significant level of KAP regarding antimicrobial (mis)use in the study. It is essential that antimicrobial stewardship programs for various stakeholders and educational programmes must be initiated to increase awareness of people on antimicrobial resistance.
抗生素耐药性（AMR）已成为全球主要的公共卫生问题之一。本横断面研究旨在确定印度奥迪沙邦蒂吉里亚（Tigiria）农村社区人群对抗生素使用和 AMR 的知识、态度和实践（KAP）。
采用基于社会人口特征、抗生素使用、对抗生素耐药性的认识、医疗保健利用和生活质量的半结构式问卷，使用电子设备和开放式数据套件（Open Data Kit）向参与者提问。采用描述性统计、独立检验和方差分析对变量进行分析。
本研究共调查了来自蒂吉里亚 25 个村庄的 1003 名参与者。约 44.47%（95%可信区间：41.36-47.60）的研究参与者听说过抗菌药物，14.75%（95%可信区间：12.65-17.13）的参与者未经处方在药店购买过抗生素。约 20.14%（95%可信区间：17.72-22.78）的参与者在完成整个疗程前停止服用抗生素。与生活质量的其他领域相比，身体领域的得分最低，受到的影响最大。生活质量评分在年龄、性别、教育程度和种族方面存在显著差异（<0.05）。
本研究记录了研究人群对抗生素（误用）使用的 KAP 水平显著。必须为各利益相关者启动抗生素管理计划和教育项目，以提高人们对抗生素耐药性的认识。
