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[自发性心绞痛发作的可能发病机制]

[Possible pathogenetic mechanisms of spontaneous stenocardia attacks].

作者信息

Ermilov L P, Kuleshova E V, Isakova T I

出版信息

Ter Arkh. 1985;57(4):92-5.

PMID:4012640
Abstract

Study of changes in the electrocardiogram during spontaneous attacks of angina pectoris has shown that out of 80 patients examined, 78 (98.6%) patients with angina pectoris at rest manifested ischemic-type changes in the end part of the ventricular complex of the ECG, whereas in 81% of the patients, rhythm and conduction abnormalities were recorded in addition. It has been established that during a spontaneous angina pectoris attack, the degree of an increase in the double product was lower while the degree of the ischemic depression of the ST segment was greater than during threshold load. Apparently, the reduction of the coronary blood flow rather than a dramatic increase in myocardial oxygen requirement plays the leading part in the pathogenesis of spontaneous attacks of angina pectoris.

摘要

对心绞痛发作时心电图变化的研究表明,在80例接受检查的患者中,78例(98.6%)静息性心绞痛患者在心电图心室复合波终末部分出现缺血型改变,而另外81%的患者还记录到节律和传导异常。已经确定,在自发性心绞痛发作期间,双乘积增加的程度较低,而ST段缺血性压低的程度大于阈负荷时。显然,冠状动脉血流减少而非心肌需氧量急剧增加在自发性心绞痛发作的发病机制中起主导作用。

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