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纽约州快速启动艾滋病毒抗逆转录病毒治疗

Rapid Start of HIV Antiretroviral Therapy in New York State.

作者信息

Wells Christopher, Driver Redd, Belanger Daniel, Boos Elizabeth M, Barkevich Jonas, Tesoriero James M

机构信息

Office of Quality Initiatives, New York State Department of Health AIDS Institute, New York, NY, USA.

Center for Program Development, Implementation, Research and Evaluation, New York State Department of Health AIDS Institute, Albany, NY, USA.

出版信息

AIDS Behav. 2025 Jun;29(6):1910-1919. doi: 10.1007/s10461-025-04658-2. Epub 2025 Mar 24.

Abstract

Rapid start of antiretroviral therapy (ART) after an HIV diagnosis is a novel approach with demonstrated benefits for HIV care. However, utilization of this approach remains poor in the United States. Using retrospective reviews of HIV clinical care data from the New York State Department of Health AIDS Institute's Quality of Care Program, we examined changes in rapid start of ART from 2019 to 2022 to assess the degree to which the rapid start model is being realized in the state. We also identified patient-level factors associated with delayed initiation and examined associations between time to treatment initiation and viral load suppression. We found that rapid initiation increased steadily across the years examined but differed depending on where patients received care and whether they were initially diagnosed by the data-reporting organization or by an external medical organization or testing center. We also found that rapid start varied across several patient-level factors, which also depended on whether patients were initially diagnosed by the data-reporting organization or by an external medical organization or testing center. Finally, 67.8% of patients who initiated ART on the same day of HIV diagnosis and 69.7% of patients who started ART within seven days of diagnosis were virally suppressed within 91 days of diagnosis, compared to 42.9% of patients who initiated ART between 31 and 91 days. Increased utilization of the rapid start model over time and strong associations between rapid start and timely viral suppression suggest that further uptake of this strategy would likely advance progress towards Ending the Epidemic and health equity goals.

摘要

在确诊感染艾滋病毒后迅速开始抗逆转录病毒疗法(ART)是一种新方法,已证明对艾滋病毒护理有益。然而,在美国,这种方法的使用率仍然很低。通过回顾纽约州卫生部艾滋病研究所护理质量项目的艾滋病毒临床护理数据,我们研究了2019年至2022年期间ART快速启动的变化,以评估该州快速启动模式的实现程度。我们还确定了与延迟启动相关的患者层面因素,并研究了开始治疗时间与病毒载量抑制之间的关联。我们发现,在所研究的几年中,快速启动稳步增加,但因患者接受护理的地点以及他们最初是由数据报告机构、外部医疗组织还是检测中心诊断而有所不同。我们还发现,快速启动在几个患者层面因素上存在差异,这也取决于患者最初是由数据报告机构、外部医疗组织还是检测中心诊断。最后,在艾滋病毒诊断当天开始接受ART治疗的患者中,67.8%在诊断后91天内实现了病毒抑制;在诊断后7天内开始接受ART治疗的患者中,69.7%在诊断后91天内实现了病毒抑制,而在诊断后31至91天开始接受ART治疗的患者中,这一比例为42.9%。随着时间的推移,快速启动模式的利用率增加,以及快速启动与及时病毒抑制之间的强烈关联表明,进一步采用这一策略可能会推动在实现“终结艾滋病流行”和健康公平目标方面取得进展。

相似文献

1
Rapid Start of HIV Antiretroviral Therapy in New York State.纽约州快速启动艾滋病毒抗逆转录病毒治疗
AIDS Behav. 2025 Jun;29(6):1910-1919. doi: 10.1007/s10461-025-04658-2. Epub 2025 Mar 24.

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