Zhong Huaiqin, Qiu Yan, Zhu Xvping, Li Jinyu, Liu Mei, Zou Zhuoqun
Gerontology Department, Shanghai Health and Medical Center, Wuxi, Jiangsu Province, China.
Medical Department, Shanghai Health and Medical Center, Wuxi, Jiangsu Province, China.
J Hum Hypertens. 2025 May;39(5):343-347. doi: 10.1038/s41371-025-01010-y. Epub 2025 Mar 24.
Hypertension (HTN) can lead to a series of target organ damage and is associated with increased cardiovascular disease incidence and mortality. Perimenopause implies an important physiological transition. Previous studies have confirmed that obesity is a risk factor for the development of HTN. Nevertheless, few studies have investigated the prevalence of HTN in perimenopausal women and the relationships between peripheral or abdominal obesity and HTN. Therefore, we analysed the influencing factors of HTN in perimenopausal working women and the correlation between different types of obesity and HTN to provide evidence for the need to prevent HTN in perimenopausal women. Perimenopausal women who underwent physical examination at Shanghai Health and Medical Center from January 2021 to October 2021 were selected as subjects. A multivariate logistic regression model was used to analyse the associations between different types of obesity and HTN in perimenopausal women. Five hundred eighty-two perimenopausal women were included in this study; 124 cases of HTN were detected (incidence rate 21.31%), 23 of which were isolated systolic HTN (18.55% of total HTN cases). Multivariate logistic regression analysis revealed that age and BMI were the influencing factors of HTN in perimenopausal women. Compared with that of perimenopausal women without peripheral obesity, HTN in overweight (OR = 1.84, 95% CI: 1.13-2.98) and peripheral obesity (OR = 4.36, 95% CI: 1.52-12.54) women increased with increasing body weight. Perimenopausal women with abdominal obesity had a greater risk of developing HTN (OR = 2.69, 95% CI: 1.16-6.21) (P < 0.05). Age and BMI are risk factors for the development of HTN in perimenopausal working women. Both abdominal obesity and peripheral obesity are positively associated with HTN in perimenopausal women. The BMI and abdominal circumference of perimenopausal women need to be monitored as early as possible to prevent obesity and reduce the occurrence of HTN.
高血压（HTN）可导致一系列靶器官损害，并与心血管疾病发病率和死亡率的增加相关。围绝经期意味着一个重要的生理转变。先前的研究已证实肥胖是高血压发生的一个危险因素。然而，很少有研究调查围绝经期女性高血压的患病率以及外周或腹部肥胖与高血压之间的关系。因此，我们分析了围绝经期职业女性高血压的影响因素以及不同类型肥胖与高血压之间的相关性，为围绝经期女性预防高血压的必要性提供依据。选取2021年1月至2021年10月在上海健康与医学中心接受体检的围绝经期女性作为研究对象。采用多因素logistic回归模型分析围绝经期女性不同类型肥胖与高血压之间的关联。本研究纳入了582名围绝经期女性；检测出124例高血压患者（发病率21.31%），其中23例为单纯收缩期高血压（占高血压病例总数的18.55%）。多因素logistic回归分析显示，年龄和体重指数是围绝经期女性高血压的影响因素。与无外周肥胖的围绝经期女性相比，超重（OR = 1.84，95%CI：1.13 - 2.98）和外周肥胖（OR = 4.36，95%CI：1.52 - 12.54）女性的高血压随着体重增加而升高。有腹部肥胖的围绝经期女性患高血压的风险更大（OR = 2.69，95%CI：1.16 - 6.21）（P < 0.05）。年龄和体重指数是围绝经期职业女性高血压发生的危险因素。腹部肥胖和外周肥胖均与围绝经期女性高血压呈正相关。需要尽早监测围绝经期女性的体重指数和腹围，以预防肥胖并降低高血压的发生。
